These experiments offer further proof of the effectiveness of clonazepam in controlling, not so much the fundamental processes of epileptic activity, as the mechanisms behind the propagation of this activity from its primary focus to other parts of the brain; the more complex these mechanisms are the more effective the drug is in controlling the fits. Similarly, it tends to inhibit possible bilateral interaction between separate foci rather than suppress either on its own. The results described, combined with previous observations, show that clonazepam is clinically most effective in the generalized forms of epilepsy or those which arise from one or more primary or secondary foci.
|Translated title of the contribution||Effects of clonazepam on the phenomena of experimental bilateral rhinencephalic epileptic activity interaction|
|Number of pages||10|
|Journal||Rivista di Neurologia|
|Publication status||Published - 1974|
ASJC Scopus subject areas
- Clinical Neurology