Fifteen patients who underwent kidney transplant were studied in order to evaluate the effects of CyA on the gastrointestinal hormonal pattern. Eight patients followed traditional therapy while seven were treated with CyA. The basal gastrinaemia values were high only in those patients treated with CyA. This might be due to: 1) an increase in hormone secretion and/or release; 2) a decreased hormone elimination probably due to nephro-hepatic toxicity of CyA; 3) an increase in prostaglandins, caused by CyA, which inhibit secretion of gastric acids.
|Number of pages||4|
|Publication status||Published - 1987|
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