Abstract
Previous data indicate that the injection of dopaminergic drugs induces changes in cerebellar 3',5'-guanosine monophosphate (cGMP) content. Accordingly, we have investigated the effects of haloperidol, sulpiride, or apomorphine on cerebellar prostaglandin (PG) concentration, a parameter related to cGMP content. Results obtained show that dopamine receptor blocking agents, such as haloperidol and sulpiride, significantly decrease cerebellar PGE2 and PGF(2α) concentrations, while opposite changes are induced by apomorphine, a dopamine receptor agonist
| Original language | English |
|---|---|
| Pages (from-to) | 1190-1191 |
| Number of pages | 2 |
| Journal | Journal of Neurochemistry |
| Volume | 41 |
| Issue number | 4 |
| Publication status | Published - 1983 |
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ASJC Scopus subject areas
- Biochemistry
- Cellular and Molecular Neuroscience
Cite this
Effects of dopaminergic drugs on cerebellar prostaglandin concentrations. / Millia, C.; Nicoletti, F.; Grasso, A. A.; Patti, F.; Condorelli, D. F.; Rapisarda, E.; Rampello, L.; Costa, G.; Scapagnini, U.
In: Journal of Neurochemistry, Vol. 41, No. 4, 1983, p. 1190-1191.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of dopaminergic drugs on cerebellar prostaglandin concentrations
AU - Millia, C.
AU - Nicoletti, F.
AU - Grasso, A. A.
AU - Patti, F.
AU - Condorelli, D. F.
AU - Rapisarda, E.
AU - Rampello, L.
AU - Costa, G.
AU - Scapagnini, U.
PY - 1983
Y1 - 1983
N2 - Previous data indicate that the injection of dopaminergic drugs induces changes in cerebellar 3',5'-guanosine monophosphate (cGMP) content. Accordingly, we have investigated the effects of haloperidol, sulpiride, or apomorphine on cerebellar prostaglandin (PG) concentration, a parameter related to cGMP content. Results obtained show that dopamine receptor blocking agents, such as haloperidol and sulpiride, significantly decrease cerebellar PGE2 and PGF(2α) concentrations, while opposite changes are induced by apomorphine, a dopamine receptor agonist
AB - Previous data indicate that the injection of dopaminergic drugs induces changes in cerebellar 3',5'-guanosine monophosphate (cGMP) content. Accordingly, we have investigated the effects of haloperidol, sulpiride, or apomorphine on cerebellar prostaglandin (PG) concentration, a parameter related to cGMP content. Results obtained show that dopamine receptor blocking agents, such as haloperidol and sulpiride, significantly decrease cerebellar PGE2 and PGF(2α) concentrations, while opposite changes are induced by apomorphine, a dopamine receptor agonist
UR - http://www.scopus.com/inward/record.url?scp=0020550406&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020550406&partnerID=8YFLogxK
M3 - Article
C2 - 6578301
AN - SCOPUS:0020550406
VL - 41
SP - 1190
EP - 1191
JO - Journal of Neurochemistry
JF - Journal of Neurochemistry
SN - 0022-3042
IS - 4
ER -