Effects of dual-chamber pacing in hypertrophic cardiomyopathy on left ventricular outflow tract obstruction and on diastolic function

S. Betocchi, M. A. Losi, F. Piscione, M. Boccalatte, L. Pace, P. Golino, P. Perrone-Filardi, C. Briguori, F. Franculli, C. Pappone, M. Salvatore, M. Chiariello

Research output: Contribution to journalArticlepeer-review

Abstract

Hypertrophic cardiomyopathy (HC) is characterized by impaired diastolic function and, in about 1/4 of patients, left ventricular (LV) outflow tract obstruction. Atrioventricular (AV) pacing diminishes LV outflow tract gradient in HC, but impairs diastolic function in the experimental animal and in different categories of patients. To investigate the effects of AV pacing on hemodynamics and LV function in obstructive HC, 16 patients with HC were studied by cardiac catheterization and simultaneous radionuclide angiography during atrial and AV pacing. The resting LV outflow tract gradient decreased with AV pacing from 60 ± 34 to 38 ± 37 mm Hg (mean ± SD; p

Original languageEnglish
Pages (from-to)498-502
Number of pages5
JournalThe American Journal of Cardiology
Volume77
Issue number7
DOIs
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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