Effects of electric and magnetic transcranial stimulation on long latency reflexes

G. Deuschl, R. Michels, A. Berardelli, E. Schenck, M. Inghilleri, C. H. Lücking

Research output: Contribution to journalArticle

93 Citations (Scopus)

Abstract

The interaction of transcranial electric and magnetic brain stimulation with electrically elicited shortand long latency reflexes (LLR) of hand and fore-arm flexor muscles has been investigated in normal subjects. In the first paradigm, the motor potential evoked in thenar muscles by transcranial stimulation was conditioned by median nerve stimulation at various conditioning-test intervals. At short intervals (electric: 5-12.5 ms, magnetic: 0-7.5 ms) facilitation occurred that corresponded to the H-reflex and at longer intervals (electric: 25-40 ms, magnetic: 22.5-35 ms) there was a facilitation corresponding to the LLR. Electric and magnetic stimulation resulted in a similar degree of facilitation. A second paradigm investigated the facilitation of the forearm flexor H-reflex by a cutaneo-muscular LLR elicited by radial superficial nerve stimulation and transcranial stimulation used separately or together. When electric and magnetic brain stimulation were compared, magnetic brain stimulation was followed by significant extrafacilitation but electric stimulation was not. This result favours an interaction between the afferent volley eliciting the LLR and transcranial magnetic stimulation most likely at supraspinal level.

Original languageEnglish
Pages (from-to)403-410
Number of pages8
JournalExperimental Brain Research
Volume83
Issue number2
DOIs
Publication statusPublished - Jan 1991

Fingerprint

Transcranial Magnetic Stimulation
Reflex
H-Reflex
Electric Stimulation
Brain
Radial Nerve
Motor Evoked Potentials
Muscles
Median Nerve
Forearm
Arm
Hand

Keywords

  • Human
  • Long latency reflexes
  • Physiology
  • Transcranial stimulation

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Effects of electric and magnetic transcranial stimulation on long latency reflexes. / Deuschl, G.; Michels, R.; Berardelli, A.; Schenck, E.; Inghilleri, M.; Lücking, C. H.

In: Experimental Brain Research, Vol. 83, No. 2, 01.1991, p. 403-410.

Research output: Contribution to journalArticle

Deuschl, G, Michels, R, Berardelli, A, Schenck, E, Inghilleri, M & Lücking, CH 1991, 'Effects of electric and magnetic transcranial stimulation on long latency reflexes', Experimental Brain Research, vol. 83, no. 2, pp. 403-410. https://doi.org/10.1007/BF00231165
Deuschl, G. ; Michels, R. ; Berardelli, A. ; Schenck, E. ; Inghilleri, M. ; Lücking, C. H. / Effects of electric and magnetic transcranial stimulation on long latency reflexes. In: Experimental Brain Research. 1991 ; Vol. 83, No. 2. pp. 403-410.
@article{7facbf1158f84a8dae12406b2a907ed8,
title = "Effects of electric and magnetic transcranial stimulation on long latency reflexes",
abstract = "The interaction of transcranial electric and magnetic brain stimulation with electrically elicited shortand long latency reflexes (LLR) of hand and fore-arm flexor muscles has been investigated in normal subjects. In the first paradigm, the motor potential evoked in thenar muscles by transcranial stimulation was conditioned by median nerve stimulation at various conditioning-test intervals. At short intervals (electric: 5-12.5 ms, magnetic: 0-7.5 ms) facilitation occurred that corresponded to the H-reflex and at longer intervals (electric: 25-40 ms, magnetic: 22.5-35 ms) there was a facilitation corresponding to the LLR. Electric and magnetic stimulation resulted in a similar degree of facilitation. A second paradigm investigated the facilitation of the forearm flexor H-reflex by a cutaneo-muscular LLR elicited by radial superficial nerve stimulation and transcranial stimulation used separately or together. When electric and magnetic brain stimulation were compared, magnetic brain stimulation was followed by significant extrafacilitation but electric stimulation was not. This result favours an interaction between the afferent volley eliciting the LLR and transcranial magnetic stimulation most likely at supraspinal level.",
keywords = "Human, Long latency reflexes, Physiology, Transcranial stimulation",
author = "G. Deuschl and R. Michels and A. Berardelli and E. Schenck and M. Inghilleri and L{\"u}cking, {C. H.}",
year = "1991",
month = "1",
doi = "10.1007/BF00231165",
language = "English",
volume = "83",
pages = "403--410",
journal = "Experimental Brain Research",
issn = "0014-4819",
publisher = "Springer Verlag",
number = "2",

}

TY - JOUR

T1 - Effects of electric and magnetic transcranial stimulation on long latency reflexes

AU - Deuschl, G.

AU - Michels, R.

AU - Berardelli, A.

AU - Schenck, E.

AU - Inghilleri, M.

AU - Lücking, C. H.

PY - 1991/1

Y1 - 1991/1

N2 - The interaction of transcranial electric and magnetic brain stimulation with electrically elicited shortand long latency reflexes (LLR) of hand and fore-arm flexor muscles has been investigated in normal subjects. In the first paradigm, the motor potential evoked in thenar muscles by transcranial stimulation was conditioned by median nerve stimulation at various conditioning-test intervals. At short intervals (electric: 5-12.5 ms, magnetic: 0-7.5 ms) facilitation occurred that corresponded to the H-reflex and at longer intervals (electric: 25-40 ms, magnetic: 22.5-35 ms) there was a facilitation corresponding to the LLR. Electric and magnetic stimulation resulted in a similar degree of facilitation. A second paradigm investigated the facilitation of the forearm flexor H-reflex by a cutaneo-muscular LLR elicited by radial superficial nerve stimulation and transcranial stimulation used separately or together. When electric and magnetic brain stimulation were compared, magnetic brain stimulation was followed by significant extrafacilitation but electric stimulation was not. This result favours an interaction between the afferent volley eliciting the LLR and transcranial magnetic stimulation most likely at supraspinal level.

AB - The interaction of transcranial electric and magnetic brain stimulation with electrically elicited shortand long latency reflexes (LLR) of hand and fore-arm flexor muscles has been investigated in normal subjects. In the first paradigm, the motor potential evoked in thenar muscles by transcranial stimulation was conditioned by median nerve stimulation at various conditioning-test intervals. At short intervals (electric: 5-12.5 ms, magnetic: 0-7.5 ms) facilitation occurred that corresponded to the H-reflex and at longer intervals (electric: 25-40 ms, magnetic: 22.5-35 ms) there was a facilitation corresponding to the LLR. Electric and magnetic stimulation resulted in a similar degree of facilitation. A second paradigm investigated the facilitation of the forearm flexor H-reflex by a cutaneo-muscular LLR elicited by radial superficial nerve stimulation and transcranial stimulation used separately or together. When electric and magnetic brain stimulation were compared, magnetic brain stimulation was followed by significant extrafacilitation but electric stimulation was not. This result favours an interaction between the afferent volley eliciting the LLR and transcranial magnetic stimulation most likely at supraspinal level.

KW - Human

KW - Long latency reflexes

KW - Physiology

KW - Transcranial stimulation

UR - http://www.scopus.com/inward/record.url?scp=0025959653&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025959653&partnerID=8YFLogxK

U2 - 10.1007/BF00231165

DO - 10.1007/BF00231165

M3 - Article

C2 - 2022246

AN - SCOPUS:0025959653

VL - 83

SP - 403

EP - 410

JO - Experimental Brain Research

JF - Experimental Brain Research

SN - 0014-4819

IS - 2

ER -