AZIONE DELLA FLUOXETINA IN PAZIENTI CON EPILESSIA FOCALE E CON EPILESSIA GENERALIZZATA SECONDARIA

Translated title of the contribution: Effects of fluoxetine treatment in patients with focal epilepsy and with secondary generalized epilepsy

G. L. Gigli, M. Diomedi, M. C E Maschio, M. G. Marciani

Research output: Contribution to journalArticlepeer-review

Abstract

Based on the evidence of its antiepileptic activity in experimental models of epilepsy, fluoxetine have been tested as an add-on drug in the treatment of medically intractable epilepsy. Nine patients with focal or secondary generalized epilepsy received 20 mg/die of fluoxetine for one month, followed by another month with 40 mg/die in seven of them. No significant improvement was observed. In addition, side effects of the aggressive type were observed. This preliminary study does not confirm the experimental evidence of antiepileptic effectiveness of fluoxetine and discourages its use as an antidepressive agent in epileptic patients.

Translated title of the contributionEffects of fluoxetine treatment in patients with focal epilepsy and with secondary generalized epilepsy
Original languageItalian
Pages (from-to)281-282
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number79-80
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Clinical Neurology

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