TY - JOUR
T1 - Effects of hormone replacement therapy or raloxifene on ambulatory blood pressure and arterial stiffness in treated hypertensive postmenopausal women
AU - Da Costa, Lílian Soares
AU - De Oliveira, Monica Amorim
AU - Rubim, Valéria Siqueira Martins
AU - Wajngarten, Maurício
AU - Aldrighi, José Mendes
AU - Rosano, Giuseppe M.
AU - Neto, Cantidio Drumond
AU - Gebara, Otavio Celso Eluf
PY - 2004/12/1
Y1 - 2004/12/1
N2 - The administration of oral raloxifene in 30 postmenopausal hypertensive women was evaluated to demonstrate its effect on arterial stiffness. Casual and ambulatory blood pressure (BP) and pulse-wave velocity (PWV) data were obtained before and after patients received raloxifene, estrogen-progestin replacement therapy, or placebo in a randomized crossover study. It was shown that the 2 therapies decreased BP and carotid-femoral PWV, and the effect of raloxifene on vascular compliance was independent of the effects on BP.
AB - The administration of oral raloxifene in 30 postmenopausal hypertensive women was evaluated to demonstrate its effect on arterial stiffness. Casual and ambulatory blood pressure (BP) and pulse-wave velocity (PWV) data were obtained before and after patients received raloxifene, estrogen-progestin replacement therapy, or placebo in a randomized crossover study. It was shown that the 2 therapies decreased BP and carotid-femoral PWV, and the effect of raloxifene on vascular compliance was independent of the effects on BP.
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U2 - 10.1016/j.amjcard.2004.07.153
DO - 10.1016/j.amjcard.2004.07.153
M3 - Article
C2 - 15566926
AN - SCOPUS:9344257290
VL - 94
SP - 1453
EP - 1456
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 11
ER -