Effects of hormone replacement therapy or raloxifene on ambulatory blood pressure and arterial stiffness in treated hypertensive postmenopausal women

Lílian Soares Da Costa, Monica Amorim De Oliveira, Valéria Siqueira Martins Rubim, Maurício Wajngarten, José Mendes Aldrighi, Giuseppe M. Rosano, Cantidio Drumond Neto, Otavio Celso Eluf Gebara

Research output: Contribution to journalArticlepeer-review

Abstract

The administration of oral raloxifene in 30 postmenopausal hypertensive women was evaluated to demonstrate its effect on arterial stiffness. Casual and ambulatory blood pressure (BP) and pulse-wave velocity (PWV) data were obtained before and after patients received raloxifene, estrogen-progestin replacement therapy, or placebo in a randomized crossover study. It was shown that the 2 therapies decreased BP and carotid-femoral PWV, and the effect of raloxifene on vascular compliance was independent of the effects on BP.

Original languageEnglish
Pages (from-to)1453-1456
Number of pages4
JournalThe American Journal of Cardiology
Volume94
Issue number11
DOIs
Publication statusPublished - Dec 1 2004

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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