TY - JOUR
T1 - Effects of isolation on activity, reactivity, excitability and aggressive behavior in two inbred strains of mice
AU - Siegfried, Bert
AU - Alleva, Enrico
AU - Oliverio, Alberto
AU - Puglisiallegra, Stefano
PY - 1981
Y1 - 1981
N2 - In order to investigate mechanisms of isolation-induced aggressive behavior, inbred mice of the C57BL/6 and DBA/2 strains were individually housed over a period of 8 weeks. In the DBA/2 strain only, isolation was followed by a clear increase in activity (Animex), reactivity (reactions upon tactile body stimulation), excitability (duration of EEG desynchronization elicited by tactile stimulation of the thorax area under urethane anesthesia) and intermale aggression (biting and fighting responses). The use of inbred strains of mice proved to be a useful tool for the examination of the relationship between various parameters. It is concluded that there are no clear correlations between activity, reactivity and aggressive behavior and that the resulting aggressive responses in the DBA/2 strain are likely due to the increase of excitability.
AB - In order to investigate mechanisms of isolation-induced aggressive behavior, inbred mice of the C57BL/6 and DBA/2 strains were individually housed over a period of 8 weeks. In the DBA/2 strain only, isolation was followed by a clear increase in activity (Animex), reactivity (reactions upon tactile body stimulation), excitability (duration of EEG desynchronization elicited by tactile stimulation of the thorax area under urethane anesthesia) and intermale aggression (biting and fighting responses). The use of inbred strains of mice proved to be a useful tool for the examination of the relationship between various parameters. It is concluded that there are no clear correlations between activity, reactivity and aggressive behavior and that the resulting aggressive responses in the DBA/2 strain are likely due to the increase of excitability.
KW - activity
KW - aggression
KW - C57BL/6 mouse
KW - DBA/2 mouse
KW - excitability
KW - isolation
KW - reactivity
UR - http://www.scopus.com/inward/record.url?scp=0019365401&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019365401&partnerID=8YFLogxK
U2 - 10.1016/0166-4328(81)90056-5
DO - 10.1016/0166-4328(81)90056-5
M3 - Article
C2 - 7195727
AN - SCOPUS:0019365401
VL - 2
SP - 211
EP - 218
JO - Behavioural Brain Research
JF - Behavioural Brain Research
SN - 0166-4328
IS - 2
ER -