Effects of long-term football training on the expression profile of genes involved in muscle oxidative metabolism

A. Alfieri, D. Martone, M. B. Randers, G. Labruna, A. Mancini, J. J. Nielsen, J. Bangsbo, P. Krustrup, P. Buono

Research output: Contribution to journalArticlepeer-review

Abstract

We investigated whether long-term recreational football training affects the expression of health-related biochemical and molecular markers in healthy untrained subjects.Five untrained healthy men trained for 1h 2.4times/week for 12 weeks and 1.3times/week for another 52weeks. Blood samples and a muscle biopsy from the vastus lateralis were collected at T0 (pre intervention) and at T1 (post intervention). Gene expression was measured by RTqPCR on RNA extracted from muscle biopsies. The expression levels of the genes principally involved in energy metabolism (PPARγ, adiponectin, AMPKα1/α2, TFAM, NAMPT, PGC1α and SIRT1) were measured at T0 and T1. Up-regulation of PPARγ (p

Original languageEnglish
Pages (from-to)43-47
Number of pages5
JournalMolecular and Cellular Probes
Volume29
Issue number1
DOIs
Publication statusPublished - Feb 1 2015

Keywords

  • Football
  • LV-HIT
  • Messenger expression
  • Muscle biopsies
  • Recreational training

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

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