Effects of long-term football training on the expression profile of genes involved in muscle oxidative metabolism

A. Alfieri, D. Martone, M. B. Randers, G. Labruna, A. Mancini, J. J. Nielsen, J. Bangsbo, P. Krustrup, P. Buono

Research output: Contribution to journalArticle

Abstract

We investigated whether long-term recreational football training affects the expression of health-related biochemical and molecular markers in healthy untrained subjects.Five untrained healthy men trained for 1h 2.4times/week for 12 weeks and 1.3times/week for another 52weeks. Blood samples and a muscle biopsy from the vastus lateralis were collected at T0 (pre intervention) and at T1 (post intervention). Gene expression was measured by RTqPCR on RNA extracted from muscle biopsies. The expression levels of the genes principally involved in energy metabolism (PPARγ, adiponectin, AMPKα1/α2, TFAM, NAMPT, PGC1α and SIRT1) were measured at T0 and T1. Up-regulation of PPARγ (p

Original languageEnglish
Pages (from-to)43-47
Number of pages5
JournalMolecular and Cellular Probes
Volume29
Issue number1
DOIs
Publication statusPublished - Feb 1 2015

Fingerprint

Peroxisome Proliferator-Activated Receptors
Football
Transcriptome
Biopsy
Gene Expression
Muscles
Adiponectin
Quadriceps Muscle
Energy Metabolism
Healthy Volunteers
Up-Regulation
Biomarkers
RNA
Health

Keywords

  • Football
  • LV-HIT
  • Messenger expression
  • Muscle biopsies
  • Recreational training

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Effects of long-term football training on the expression profile of genes involved in muscle oxidative metabolism. / Alfieri, A.; Martone, D.; Randers, M. B.; Labruna, G.; Mancini, A.; Nielsen, J. J.; Bangsbo, J.; Krustrup, P.; Buono, P.

In: Molecular and Cellular Probes, Vol. 29, No. 1, 01.02.2015, p. 43-47.

Research output: Contribution to journalArticle

Alfieri, A. ; Martone, D. ; Randers, M. B. ; Labruna, G. ; Mancini, A. ; Nielsen, J. J. ; Bangsbo, J. ; Krustrup, P. ; Buono, P. / Effects of long-term football training on the expression profile of genes involved in muscle oxidative metabolism. In: Molecular and Cellular Probes. 2015 ; Vol. 29, No. 1. pp. 43-47.
@article{5a11f8e806bb49f6a74c05fa9645afd1,
title = "Effects of long-term football training on the expression profile of genes involved in muscle oxidative metabolism",
abstract = "We investigated whether long-term recreational football training affects the expression of health-related biochemical and molecular markers in healthy untrained subjects.Five untrained healthy men trained for 1h 2.4times/week for 12 weeks and 1.3times/week for another 52weeks. Blood samples and a muscle biopsy from the vastus lateralis were collected at T0 (pre intervention) and at T1 (post intervention). Gene expression was measured by RTqPCR on RNA extracted from muscle biopsies. The expression levels of the genes principally involved in energy metabolism (PPARγ, adiponectin, AMPKα1/α2, TFAM, NAMPT, PGC1α and SIRT1) were measured at T0 and T1. Up-regulation of PPARγ (p",
keywords = "Football, LV-HIT, Messenger expression, Muscle biopsies, Recreational training",
author = "A. Alfieri and D. Martone and Randers, {M. B.} and G. Labruna and A. Mancini and Nielsen, {J. J.} and J. Bangsbo and P. Krustrup and P. Buono",
year = "2015",
month = "2",
day = "1",
doi = "10.1016/j.mcp.2014.11.003",
language = "English",
volume = "29",
pages = "43--47",
journal = "Molecular and Cellular Probes",
issn = "0890-8508",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - Effects of long-term football training on the expression profile of genes involved in muscle oxidative metabolism

AU - Alfieri, A.

AU - Martone, D.

AU - Randers, M. B.

AU - Labruna, G.

AU - Mancini, A.

AU - Nielsen, J. J.

AU - Bangsbo, J.

AU - Krustrup, P.

AU - Buono, P.

PY - 2015/2/1

Y1 - 2015/2/1

N2 - We investigated whether long-term recreational football training affects the expression of health-related biochemical and molecular markers in healthy untrained subjects.Five untrained healthy men trained for 1h 2.4times/week for 12 weeks and 1.3times/week for another 52weeks. Blood samples and a muscle biopsy from the vastus lateralis were collected at T0 (pre intervention) and at T1 (post intervention). Gene expression was measured by RTqPCR on RNA extracted from muscle biopsies. The expression levels of the genes principally involved in energy metabolism (PPARγ, adiponectin, AMPKα1/α2, TFAM, NAMPT, PGC1α and SIRT1) were measured at T0 and T1. Up-regulation of PPARγ (p

AB - We investigated whether long-term recreational football training affects the expression of health-related biochemical and molecular markers in healthy untrained subjects.Five untrained healthy men trained for 1h 2.4times/week for 12 weeks and 1.3times/week for another 52weeks. Blood samples and a muscle biopsy from the vastus lateralis were collected at T0 (pre intervention) and at T1 (post intervention). Gene expression was measured by RTqPCR on RNA extracted from muscle biopsies. The expression levels of the genes principally involved in energy metabolism (PPARγ, adiponectin, AMPKα1/α2, TFAM, NAMPT, PGC1α and SIRT1) were measured at T0 and T1. Up-regulation of PPARγ (p

KW - Football

KW - LV-HIT

KW - Messenger expression

KW - Muscle biopsies

KW - Recreational training

UR - http://www.scopus.com/inward/record.url?scp=84923540124&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84923540124&partnerID=8YFLogxK

U2 - 10.1016/j.mcp.2014.11.003

DO - 10.1016/j.mcp.2014.11.003

M3 - Article

C2 - 25444938

AN - SCOPUS:84923540124

VL - 29

SP - 43

EP - 47

JO - Molecular and Cellular Probes

JF - Molecular and Cellular Probes

SN - 0890-8508

IS - 1

ER -