Effects of long-term football training on the expression profile of genes involved in muscle oxidative metabolism

A. Alfieri; D. Martone; M. B. Randers; G. Labruna; A. Mancini; J. J. Nielsen; J. Bangsbo; P. Krustrup; P. Buono

doi:10.1016/j.mcp.2014.11.003

Effects of long-term football training on the expression profile of genes involved in muscle oxidative metabolism

A. Alfieri, D. Martone, M. B. Randers, G. Labruna, A. Mancini, J. J. Nielsen, J. Bangsbo, P. Krustrup, P. Buono

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Abstract

We investigated whether long-term recreational football training affects the expression of health-related biochemical and molecular markers in healthy untrained subjects.Five untrained healthy men trained for 1h 2.4times/week for 12 weeks and 1.3times/week for another 52weeks. Blood samples and a muscle biopsy from the vastus lateralis were collected at T0 (pre intervention) and at T1 (post intervention). Gene expression was measured by RTqPCR on RNA extracted from muscle biopsies. The expression levels of the genes principally involved in energy metabolism (PPARγ, adiponectin, AMPKα1/α2, TFAM, NAMPT, PGC1α and SIRT1) were measured at T0 and T1. Up-regulation of PPARγ (p

Original language	English
Pages (from-to)	43-47
Number of pages	5
Journal	Molecular and Cellular Probes
Volume	29
Issue number	1
DOIs	https://doi.org/10.1016/j.mcp.2014.11.003
Publication status	Published - Feb 1 2015

Keywords

Football
LV-HIT
Messenger expression
Muscle biopsies
Recreational training

ASJC Scopus subject areas

Cell Biology
Molecular Biology

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10.1016/j.mcp.2014.11.003

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title = "Effects of long-term football training on the expression profile of genes involved in muscle oxidative metabolism",

abstract = "We investigated whether long-term recreational football training affects the expression of health-related biochemical and molecular markers in healthy untrained subjects.Five untrained healthy men trained for 1h 2.4times/week for 12 weeks and 1.3times/week for another 52weeks. Blood samples and a muscle biopsy from the vastus lateralis were collected at T0 (pre intervention) and at T1 (post intervention). Gene expression was measured by RTqPCR on RNA extracted from muscle biopsies. The expression levels of the genes principally involved in energy metabolism (PPARγ, adiponectin, AMPKα1/α2, TFAM, NAMPT, PGC1α and SIRT1) were measured at T0 and T1. Up-regulation of PPARγ (p",

keywords = "Football, LV-HIT, Messenger expression, Muscle biopsies, Recreational training",

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AU - Alfieri, A.

AU - Martone, D.

AU - Randers, M. B.

AU - Labruna, G.

AU - Mancini, A.

AU - Nielsen, J. J.

AU - Bangsbo, J.

AU - Krustrup, P.

AU - Buono, P.

PY - 2015/2/1

Y1 - 2015/2/1

N2 - We investigated whether long-term recreational football training affects the expression of health-related biochemical and molecular markers in healthy untrained subjects.Five untrained healthy men trained for 1h 2.4times/week for 12 weeks and 1.3times/week for another 52weeks. Blood samples and a muscle biopsy from the vastus lateralis were collected at T0 (pre intervention) and at T1 (post intervention). Gene expression was measured by RTqPCR on RNA extracted from muscle biopsies. The expression levels of the genes principally involved in energy metabolism (PPARγ, adiponectin, AMPKα1/α2, TFAM, NAMPT, PGC1α and SIRT1) were measured at T0 and T1. Up-regulation of PPARγ (p

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KW - Messenger expression

KW - Muscle biopsies

KW - Recreational training

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Effects of long-term football training on the expression profile of genes involved in muscle oxidative metabolism

Abstract

Keywords

ASJC Scopus subject areas

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