Effects of Mössbauer radiation on bone marrow cultures

I. Ortalli, G. Pedrazzi, K. Jiang, X. Zhang, C. Carlo-Stella, L. Mangoni, V. Rizzoli

Research output: Contribution to journalArticlepeer-review

Abstract

A low radiation dose approach to cell eradication would be highly desirable in cancer treatments in order to reduce the side ellects of conventional radiotherapy. In the present work we present a preliminary study on coltures of bone marrow mononuclear cells collected from normal subjects and patients with chronic myelogenous leukaemia (CML). Hematin (104, 10-3, 10°M) has been added to mattow culture cells which were then irradiated with a 3.7 GBq (100 mCi)57Co/Rh Mossbauer source for 4 hours. Significant inbibition has been observed on the cell growth due to hematin and irradiatron.

Original languageEnglish
Pages (from-to)1267-1270
Number of pages4
JournalHyperfine Interactions
Volume71
Issue number1-4
DOIs
Publication statusPublished - Apr 1992

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Nuclear and High Energy Physics
  • Condensed Matter Physics
  • Physics and Astronomy(all)
  • Electronic, Optical and Magnetic Materials

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