Effects of malnutrition on the acute phase response of plasma proteins in patients undergoing total gastrectomy

L. Dominioni; R. Dionigi; V. Jemos; E. Bonomi; G. V. Melzi d'Eril; P. Dal Ri

doi:10.1016/0261-5614(83)90008-0

Effects of malnutrition on the acute phase response of plasma proteins in patients undergoing total gastrectomy

L. Dominioni, R. Dionigi, V. Jemos, E. Bonomi, G. V. Melzi d'Eril, P. Dal Ri

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

The serum level of six acute phase proteins (APP) has been evaluated preoperatively and for a few days in the postoperative period. Thirty patients undergoing total gastrectomy for gastric cancer have been studied in two subgroups according to their nutritional status. Those with gastric cancer had significantly higher baseline serum levels of alpha 1 acid glycoprotein (α1AGP) and C-reactive protein (CRP) than a control group. Malnourished patients also had reduced acute phase response for α1AGP and alpha 1 antitrypsin (α1AT) a higher increase of CRP and fibrinogen, and a lower decrease for transferrin and retinol binding protein (RBP).

Original language	English
Pages (from-to)	297-303
Number of pages	7
Journal	Clinical Nutrition
Volume	1
Issue number	4
DOIs	https://doi.org/10.1016/0261-5614(83)90008-0
Publication status	Published - 1983

ASJC Scopus subject areas

Medicine (miscellaneous)
Critical Care and Intensive Care Medicine
Endocrinology, Diabetes and Metabolism
Gastroenterology
Health Professions(all)

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abstract = "The serum level of six acute phase proteins (APP) has been evaluated preoperatively and for a few days in the postoperative period. Thirty patients undergoing total gastrectomy for gastric cancer have been studied in two subgroups according to their nutritional status. Those with gastric cancer had significantly higher baseline serum levels of alpha 1 acid glycoprotein (α1AGP) and C-reactive protein (CRP) than a control group. Malnourished patients also had reduced acute phase response for α1AGP and alpha 1 antitrypsin (α1AT) a higher increase of CRP and fibrinogen, and a lower decrease for transferrin and retinol binding protein (RBP).",

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AU - Dominioni, L.

AU - Dionigi, R.

AU - Jemos, V.

AU - Bonomi, E.

AU - Melzi d'Eril, G. V.

AU - Dal Ri, P.

PY - 1983

Y1 - 1983

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AB - The serum level of six acute phase proteins (APP) has been evaluated preoperatively and for a few days in the postoperative period. Thirty patients undergoing total gastrectomy for gastric cancer have been studied in two subgroups according to their nutritional status. Those with gastric cancer had significantly higher baseline serum levels of alpha 1 acid glycoprotein (α1AGP) and C-reactive protein (CRP) than a control group. Malnourished patients also had reduced acute phase response for α1AGP and alpha 1 antitrypsin (α1AT) a higher increase of CRP and fibrinogen, and a lower decrease for transferrin and retinol binding protein (RBP).

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Effects of malnutrition on the acute phase response of plasma proteins in patients undergoing total gastrectomy

Abstract

ASJC Scopus subject areas

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