EFFETTI DEL METOPROLOLO SULLA FUNZIONE MIOCARDICA DURANTE LO SFORZO IN SOGGETTI IPERTESI

Translated title of the contribution: Effects of metoprolol on myocardial performance in hypertensive patients during exercise

G. Ferro, B. Ricciardelli, M. Volpe, M. Tari, B. Trimarco, F. Rengo, M. Condorelli

Research output: Contribution to journalArticlepeer-review

Abstract

In this study the effects of metoprolol administration (200 mg daily per os) to 20 hypertensive subjects (WHO stage I and II), as a 20-days course, on heart rate (HR), systolic blood pressure (BP) and myocardial performance evaluated by systolic time intervals, were studied both at rest and during exercise. This treatment was able to reduce significantly HR and BP in all the patients, both at rest and during exercise. After the 20 days treatment, the left ventricular ejection time corrected for HR (LVETc) did not show any significant change both at rest and during exercise. On the other hand, the pre-ejection period (PEP) changed at rest in all the subjects studied after metoprolol treatment, but increased significantly during exercise only in patients in the I WHO class and only at the highest work load (at 70 watts, from 63±2 to 78±7 msec, P

Translated title of the contributionEffects of metoprolol on myocardial performance in hypertensive patients during exercise
Original languageItalian
Pages (from-to)1171-1178
Number of pages8
JournalGiornale Italiano di Cardiologia
Volume10
Issue number9
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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