Effects of motor cortex rTMS on lower urinary tract dysfunction in multiple sclerosis

Diego Centonze, F. Petta, V. Versace, S. Rossi, F. Torelli, C. Prosperetti, St Rossi, G. A. Marfia, G. Bernardi, G. Koch, R. Miano, L. Boffa, E. Finazzi-Agrò

Research output: Contribution to journalArticle

Abstract

We tested the effects of 5-Hz rTMS over the motor cortex in multiple sclerosis (MS) subjects complaining of lower urinary tract symptoms either in the filling or voiding phase. Our data show that motor cortex stimulation for five consecutive days over two weeks ameliorates the voiding phase of the micturition cycle, suggesting that enhancing corticospinal tract excitability might be useful to ameliorate detrusor contraction and/or urethral sphincter relaxation in MS patients with bladder dysfunction.

Original languageEnglish
Pages (from-to)269-271
Number of pages3
JournalMultiple Sclerosis Journal
Volume13
Issue number2
DOIs
Publication statusPublished - Mar 2007

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Keywords

  • Cortex
  • Detrusor overactivity
  • Motor cortex
  • rTMS
  • Voiding dysfunction

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Centonze, D., Petta, F., Versace, V., Rossi, S., Torelli, F., Prosperetti, C., Rossi, S., Marfia, G. A., Bernardi, G., Koch, G., Miano, R., Boffa, L., & Finazzi-Agrò, E. (2007). Effects of motor cortex rTMS on lower urinary tract dysfunction in multiple sclerosis. Multiple Sclerosis Journal, 13(2), 269-271. https://doi.org/10.1177/1352458506070729