Effects of osteopathic manipulative treatment on patients with multiple sclerosis: A pilot study

Bruno Porcari, Margherita Russo, Antonino Naro, Cristian La Via, Massimo Pullia, Maria Accorinti, Rosaria De Luca, Rocco Salvatore Calabrò

Research output: Contribution to journalArticlepeer-review


Objectives: To describe the effects of osteopathic manipulative treatment in patients affected by Multiple Sclerosis (MS). Design and setting: This is a pilot study involving 20 MS patients attending the IRCCS Neurolesi “Bonino-Pulejo” Messina, Italy. Intervention: The clinical evaluation was performed before starting rehabilitation treatment (T0) and after 8 weeks of treatment (T1). The CG sample undergo a conventional rehabilitation training (CRT), 5 times/week for 60 min (for a total of 40 sessions), the EG performed the same CRT (but with a different frequency, i.e. 3 times/week, for a total of 24 sessions) and a specific OMT 2 times/week for 60 min (for a total of 16 sessions). Main outcome measures: We analyzed the scores recorded in the following main scales: Expanded Disability Status Scale (EDSS), 10 m walking test (10mWT), Hamilton anxiety rating scale (HRS-A), and the Fatigue severity scale (FSS). Results: Our data showed a reduction in the FSS score for the EG (40 ± 1,41 at T0 vs 37 ± 2,32 at T1; p = 0.04) but not in the CG (41 ± 2,41 at TO vs 39 ± 2,6 at T1) with an intergroup difference p < 0.00. An improvement of HRS-A and 10mWT was also detected in the EG. Conclusions: Our data raise idea that OMT might be useful in rehabilitative setting in MS patients, with particular regard to anxiety and fatigue.

Original languageEnglish
Pages (from-to)154-156
Number of pages3
JournalComplementary Therapies in Medicine
Publication statusPublished - Apr 2019


  • Anxiety
  • Fatigue
  • Osteopathy
  • Physiotherapy

ASJC Scopus subject areas

  • Complementary and Manual Therapy
  • Complementary and alternative medicine
  • Advanced and Specialised Nursing


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