Effects of particulate air pollution on blood pressure in a highly exposed population in Beijing, China: A repeated-measure study

Andrea Baccarelli, Francesco Barretta, Chang Dou, Xiao Zhang, John P. McCracken, Anaité Díaz, Pier Bertazzi, Joel Schwartz, Sheng Wang, Lifang Hou

Research output: Contribution to journalArticle

Abstract

Background: Particulate Matter (PM) exposure is critical in Beijing due to high population density and rapid increase in vehicular traffic. PM effects on blood pressure (BP) have been investigated as a mechanism mediating cardiovascular risks, but results are still inconsistent. The purpose of our study is to determine the effects of ambient and personal PM exposure on BP. Methods. Before the 2008 Olympic Games (June 15-July 27), we examined 60 truck drivers and 60 office workers on two days, 1-2 weeks apart (n = 240). We obtained standardized measures of post-work BP. Exposure assessment included personal PM 2.5and Elemental Carbon (EC, a tracer of traffic particles) measured using portable monitors during work hours; and ambient PM 10averaged over 1-8 days pre-examination. We examined associations of exposures (exposure group, personal PM 2.5/EC, ambient PM 10) with BP controlling for multiple covariates. Results: Mean personal PM 2.5was 94.6 g/m 3 (SD = 64.9) in office workers and 126.8 (SD = 68.8) in truck drivers (p-value <0.001). In all participants combined, a 10 g/m 3 increase in 8-day ambient PM 10was associated with BP increments of 0.98 (95%CI 0.34; 1.61; p-value = 0.003), 0.71 (95%CI 0.18; 1.24; p-value = 0.01), and 0.81 (95%CI 0.31; 1.30; p-value = 0.002) mmHg for systolic, diastolic, and mean BP, respectively. BP was not significantly different between the two groups (p-value > 0.14). Personal PM 2.5and EC during work hours were not associated with increased BP. Conclusions: Our results indicate delayed effects of ambient PM 10on BP. Lack of associations with exposure groups and personal PM 2.5/EC indicates that PM effects are related to background levels of pollution in Beijing, and not specifically to work-related exposure.

Original languageEnglish
Article number108
JournalEnvironmental Health: A Global Access Science Source
Volume10
Issue number1
DOIs
Publication statusPublished - 2011

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Particulate Matter
Air Pollution
China
Blood Pressure
Population
Motor Vehicles
Beijing
Population Density
Carbon

Keywords

  • Blood Pressure
  • China
  • Particulate Matter
  • Personal Monitoring
  • Traffic Pollution

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Public Health, Environmental and Occupational Health
  • Medicine(all)

Cite this

Effects of particulate air pollution on blood pressure in a highly exposed population in Beijing, China : A repeated-measure study. / Baccarelli, Andrea; Barretta, Francesco; Dou, Chang; Zhang, Xiao; McCracken, John P.; Díaz, Anaité; Bertazzi, Pier; Schwartz, Joel; Wang, Sheng; Hou, Lifang.

In: Environmental Health: A Global Access Science Source, Vol. 10, No. 1, 108, 2011.

Research output: Contribution to journalArticle

Baccarelli, Andrea ; Barretta, Francesco ; Dou, Chang ; Zhang, Xiao ; McCracken, John P. ; Díaz, Anaité ; Bertazzi, Pier ; Schwartz, Joel ; Wang, Sheng ; Hou, Lifang. / Effects of particulate air pollution on blood pressure in a highly exposed population in Beijing, China : A repeated-measure study. In: Environmental Health: A Global Access Science Source. 2011 ; Vol. 10, No. 1.
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abstract = "Background: Particulate Matter (PM) exposure is critical in Beijing due to high population density and rapid increase in vehicular traffic. PM effects on blood pressure (BP) have been investigated as a mechanism mediating cardiovascular risks, but results are still inconsistent. The purpose of our study is to determine the effects of ambient and personal PM exposure on BP. Methods. Before the 2008 Olympic Games (June 15-July 27), we examined 60 truck drivers and 60 office workers on two days, 1-2 weeks apart (n = 240). We obtained standardized measures of post-work BP. Exposure assessment included personal PM 2.5and Elemental Carbon (EC, a tracer of traffic particles) measured using portable monitors during work hours; and ambient PM 10averaged over 1-8 days pre-examination. We examined associations of exposures (exposure group, personal PM 2.5/EC, ambient PM 10) with BP controlling for multiple covariates. Results: Mean personal PM 2.5was 94.6 g/m 3 (SD = 64.9) in office workers and 126.8 (SD = 68.8) in truck drivers (p-value <0.001). In all participants combined, a 10 g/m 3 increase in 8-day ambient PM 10was associated with BP increments of 0.98 (95{\%}CI 0.34; 1.61; p-value = 0.003), 0.71 (95{\%}CI 0.18; 1.24; p-value = 0.01), and 0.81 (95{\%}CI 0.31; 1.30; p-value = 0.002) mmHg for systolic, diastolic, and mean BP, respectively. BP was not significantly different between the two groups (p-value > 0.14). Personal PM 2.5and EC during work hours were not associated with increased BP. Conclusions: Our results indicate delayed effects of ambient PM 10on BP. Lack of associations with exposure groups and personal PM 2.5/EC indicates that PM effects are related to background levels of pollution in Beijing, and not specifically to work-related exposure.",
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T1 - Effects of particulate air pollution on blood pressure in a highly exposed population in Beijing, China

T2 - A repeated-measure study

AU - Baccarelli, Andrea

AU - Barretta, Francesco

AU - Dou, Chang

AU - Zhang, Xiao

AU - McCracken, John P.

AU - Díaz, Anaité

AU - Bertazzi, Pier

AU - Schwartz, Joel

AU - Wang, Sheng

AU - Hou, Lifang

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N2 - Background: Particulate Matter (PM) exposure is critical in Beijing due to high population density and rapid increase in vehicular traffic. PM effects on blood pressure (BP) have been investigated as a mechanism mediating cardiovascular risks, but results are still inconsistent. The purpose of our study is to determine the effects of ambient and personal PM exposure on BP. Methods. Before the 2008 Olympic Games (June 15-July 27), we examined 60 truck drivers and 60 office workers on two days, 1-2 weeks apart (n = 240). We obtained standardized measures of post-work BP. Exposure assessment included personal PM 2.5and Elemental Carbon (EC, a tracer of traffic particles) measured using portable monitors during work hours; and ambient PM 10averaged over 1-8 days pre-examination. We examined associations of exposures (exposure group, personal PM 2.5/EC, ambient PM 10) with BP controlling for multiple covariates. Results: Mean personal PM 2.5was 94.6 g/m 3 (SD = 64.9) in office workers and 126.8 (SD = 68.8) in truck drivers (p-value <0.001). In all participants combined, a 10 g/m 3 increase in 8-day ambient PM 10was associated with BP increments of 0.98 (95%CI 0.34; 1.61; p-value = 0.003), 0.71 (95%CI 0.18; 1.24; p-value = 0.01), and 0.81 (95%CI 0.31; 1.30; p-value = 0.002) mmHg for systolic, diastolic, and mean BP, respectively. BP was not significantly different between the two groups (p-value > 0.14). Personal PM 2.5and EC during work hours were not associated with increased BP. Conclusions: Our results indicate delayed effects of ambient PM 10on BP. Lack of associations with exposure groups and personal PM 2.5/EC indicates that PM effects are related to background levels of pollution in Beijing, and not specifically to work-related exposure.

AB - Background: Particulate Matter (PM) exposure is critical in Beijing due to high population density and rapid increase in vehicular traffic. PM effects on blood pressure (BP) have been investigated as a mechanism mediating cardiovascular risks, but results are still inconsistent. The purpose of our study is to determine the effects of ambient and personal PM exposure on BP. Methods. Before the 2008 Olympic Games (June 15-July 27), we examined 60 truck drivers and 60 office workers on two days, 1-2 weeks apart (n = 240). We obtained standardized measures of post-work BP. Exposure assessment included personal PM 2.5and Elemental Carbon (EC, a tracer of traffic particles) measured using portable monitors during work hours; and ambient PM 10averaged over 1-8 days pre-examination. We examined associations of exposures (exposure group, personal PM 2.5/EC, ambient PM 10) with BP controlling for multiple covariates. Results: Mean personal PM 2.5was 94.6 g/m 3 (SD = 64.9) in office workers and 126.8 (SD = 68.8) in truck drivers (p-value <0.001). In all participants combined, a 10 g/m 3 increase in 8-day ambient PM 10was associated with BP increments of 0.98 (95%CI 0.34; 1.61; p-value = 0.003), 0.71 (95%CI 0.18; 1.24; p-value = 0.01), and 0.81 (95%CI 0.31; 1.30; p-value = 0.002) mmHg for systolic, diastolic, and mean BP, respectively. BP was not significantly different between the two groups (p-value > 0.14). Personal PM 2.5and EC during work hours were not associated with increased BP. Conclusions: Our results indicate delayed effects of ambient PM 10on BP. Lack of associations with exposure groups and personal PM 2.5/EC indicates that PM effects are related to background levels of pollution in Beijing, and not specifically to work-related exposure.

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