Abstract
| Original language | English |
|---|---|
| Journal | Asian Journal of Andrology |
| DOIs | |
| Publication status | Published - Dec 25 2018 |
| Externally published | Yes |
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Keywords
- catch-up growth
- percutaneous treatment
- testicular hypotrophy
- testicular ultrasound
- testicular volume
- varicocele
- young adults
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Effects of percutaneous varicocele repair on testicular volume: results from a 12-month follow-up. / Sansone, A.; Fegatelli, D. A.; Pozza, C.; Fattorini, G.; Lauretta, R.; Minnetti, M.; Romanelli, F.; Lucatelli, P.; Corona, M.; Bezzi, M.; Lombardo, F.; Lenzi, A.; Gianfrilli, D.
In: Asian Journal of Andrology, 25.12.2018.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Effects of percutaneous varicocele repair on testicular volume: results from a 12-month follow-up
AU - Sansone, A.
AU - Fegatelli, D. A.
AU - Pozza, C.
AU - Fattorini, G.
AU - Lauretta, R.
AU - Minnetti, M.
AU - Romanelli, F.
AU - Lucatelli, P.
AU - Corona, M.
AU - Bezzi, M.
AU - Lombardo, F.
AU - Lenzi, A.
AU - Gianfrilli, D.
N1 - LR: 20190103; JID: 100942132; OTO: NOTNLM; 2019/01/04 06:00 [entrez]; 2019/01/04 06:00 [pubmed]; 2019/01/04 06:00 [medline]; aheadofprint
PY - 2018/12/25
Y1 - 2018/12/25
N2 - Varicocele is a common finding in men. Varicocele correction has been advocated for young patients with testicular hypotrophy, but there is a lack of morphofunctional follow-up data. We assessed whether percutaneous treatment of left varicocele is associated with testicular "catch-up growth" in the following 12 months by retrospectively reviewing data from an electronic database of 10 656 patients followed up in our clinic between 2006 and 2016. We selected all young adults (/=20% difference between left and right testicular volume at baseline, was observed in 26 (22.8%) men. Participants with LTH (mean+/-s.d.: 14.5 +/- 2.7 ml) had lower baseline testicular volume compared to those without LTH (mean+/-s.d.: 15.7 +/- 3.8 ml; P = 0.032). Repeated measures mixed models showed a significant interaction between LTH and time posttreatment when correcting for baseline left testicular volume (beta = 0.114, 95% confidence interval [CI]: 0.018-0.210, P = 0.020), resulting in a catch-up growth of up to 1.37 ml per year (95% CI: 0.221-2.516). Age at intervention was also associated with reduced testicular volume (-0.072 ml per year, 95% CI: -0.135--0.009; P = 0.024). Percutaneous treatment of left varicocele in young adults with LTH can result in catch-up growth over 1 year of follow-up. The reproductive and psychological implications of these findings need to be confirmed in longer and larger prospective studies.
AB - Varicocele is a common finding in men. Varicocele correction has been advocated for young patients with testicular hypotrophy, but there is a lack of morphofunctional follow-up data. We assessed whether percutaneous treatment of left varicocele is associated with testicular "catch-up growth" in the following 12 months by retrospectively reviewing data from an electronic database of 10 656 patients followed up in our clinic between 2006 and 2016. We selected all young adults (/=20% difference between left and right testicular volume at baseline, was observed in 26 (22.8%) men. Participants with LTH (mean+/-s.d.: 14.5 +/- 2.7 ml) had lower baseline testicular volume compared to those without LTH (mean+/-s.d.: 15.7 +/- 3.8 ml; P = 0.032). Repeated measures mixed models showed a significant interaction between LTH and time posttreatment when correcting for baseline left testicular volume (beta = 0.114, 95% confidence interval [CI]: 0.018-0.210, P = 0.020), resulting in a catch-up growth of up to 1.37 ml per year (95% CI: 0.221-2.516). Age at intervention was also associated with reduced testicular volume (-0.072 ml per year, 95% CI: -0.135--0.009; P = 0.024). Percutaneous treatment of left varicocele in young adults with LTH can result in catch-up growth over 1 year of follow-up. The reproductive and psychological implications of these findings need to be confirmed in longer and larger prospective studies.
KW - catch-up growth
KW - percutaneous treatment
KW - testicular hypotrophy
KW - testicular ultrasound
KW - testicular volume
KW - varicocele
KW - young adults
U2 - 10.4103/aja.aja_102_18 [doi]
DO - 10.4103/aja.aja_102_18 [doi]
M3 - Article
JO - Asian Journal of Andrology
JF - Asian Journal of Andrology
SN - 1008-682X
ER -