Effects of personality on metabolic control in IDDM patients

A. Orlandini, M. R. Pastore, A. Fossati, S. Clerici, A. Sergi, A. Balini, M. A. Parlangeli, C. Maffei, A. Secchi, G. Pozza

Research output: Contribution to journalArticlepeer-review


OBJECTIVE - The aim of this study was to evaluate the relationship between poor metabolic control and maladaptive personality traits (according to the Diagnostic and Statistical Manual of Mental Disorders, Third Edition-Revised) in an adult-onset insulin-dependent diabetes mellitus sample group (n = 77). RESEARCH DESIGN AND METHODS - Metabolic control was evaluated through glycosylated hemoglobin (HbA(1c)). Personality traits were assessed with the Personality Diagnostic Questionnaire-Revised, a self-administered questionnaire. Residual pancreatic secretion (fasting serum C-peptide) was also evaluated. RESULTS - Principal components analysis revealed three personality profile: 'withdrawn-suspicious' (P1), 'dramatic-dependent' (P2), and 'aggressive-irresponsible' (P3). Multiple linear regression analysis showed that C-peptide levels and P2 personality profiles were significant and independent predictors of HbA(1c) plasma levels: P2 predicted high HbA(1c) values and C-peptide predicted low HbA(1c) levels. CONCLUSIONS . These data suggest that a P2 personality profile is a significant predictor of poor metabolic control.

Original languageEnglish
Pages (from-to)206-209
Number of pages4
JournalDiabetes Care
Issue number2
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

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