Effects of physical training of the dominant arm on ipsilateral radial artery distensibility and structure

Cristina Giannattasio, Monica Failla, Alessandra Grappiolo, Ivan Calchera, Niccolò Grieco, Stefano Carugo, Marco Bigoni, Pietro Randelli, Giovanni Peretti, Giuseppe Mancia

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Background: Exercise training induces cardiovascular changes that are both generalized and restricted to the microcirculation of the tissues more actively involved in the exercise itself. Whether the local effect of exercise extends to larger arteries is unknown, however. Methods: In the right and left upper limb of 17 right-handed subjects performing an asymmetric training of the upper limbs (hammer throwers and baseball players) and 16 age-matched sedentary controls, we continuously measured radial artery diameter, distensibility and wall thickness by an echotracking and a beat-to-beat finger blood pressure device. Arterial distensibility was calculated by the arctangent model of Langewouters and expressed as continuous values from diastolic to systolic blood pressure. Measurements were made: (1) in baseline conditions; (2) after release from prolonged proximal ischaemia; and (3) after an increase in radial artery blood flow caused by a short (4 min) distal ischaemia to determine the endothelial involvement in the training-induced change in arterial distensibility. Results: In athletes the radial artery distensibility was markedly greater in the right than in the left arm, the latter showing values slightly greater than those seen in the two arms of sedentary subjects. In both arms and groups radial artery distensibility increased markedly after prolonged ischaemia, the between arm and group differences being preserved, however. The radial artery response to distal short ischaemia was, on the other hand, similar in the two arms of the athletes, although greater in these subjects than in the sedentary ones. Radial artery wall thickness was greater in the trained than in the untrained arm of athletes, both values being greater than in sedentary subjects. Conclusions: Asymmetrical training of the upper limbs is accompanied by a greater distensibility of the middle-sized arteries of the more trained side. This is not associated with asymmetrical changes in endothelial structure or function. It is associated with a greater wall thickness in the trained side, suggesting that, at least in part, a training-induced asymmetrical change in wall structure (possibly with a predominance of more distensible tissues such as elastine and smooth muscle) is responsible.

Original languageEnglish
Pages (from-to)71-77
Number of pages7
JournalJournal of Hypertension
Volume19
Issue number1
DOIs
Publication statusPublished - 2001

Fingerprint

Radial Artery
Arm
Ischemia
Upper Extremity
Athletes
Exercise
Blood Pressure
Arteries
Baseball
Microcirculation
Fingers
Smooth Muscle
Equipment and Supplies

Keywords

  • Arterial distensibility
  • Arterial function
  • Athletes
  • Endothelium
  • Physical exercise
  • Physical training

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology

Cite this

Giannattasio, C., Failla, M., Grappiolo, A., Calchera, I., Grieco, N., Carugo, S., ... Mancia, G. (2001). Effects of physical training of the dominant arm on ipsilateral radial artery distensibility and structure. Journal of Hypertension, 19(1), 71-77. https://doi.org/10.1097/00004872-200101000-00010

Effects of physical training of the dominant arm on ipsilateral radial artery distensibility and structure. / Giannattasio, Cristina; Failla, Monica; Grappiolo, Alessandra; Calchera, Ivan; Grieco, Niccolò; Carugo, Stefano; Bigoni, Marco; Randelli, Pietro; Peretti, Giovanni; Mancia, Giuseppe.

In: Journal of Hypertension, Vol. 19, No. 1, 2001, p. 71-77.

Research output: Contribution to journalArticle

Giannattasio, C, Failla, M, Grappiolo, A, Calchera, I, Grieco, N, Carugo, S, Bigoni, M, Randelli, P, Peretti, G & Mancia, G 2001, 'Effects of physical training of the dominant arm on ipsilateral radial artery distensibility and structure', Journal of Hypertension, vol. 19, no. 1, pp. 71-77. https://doi.org/10.1097/00004872-200101000-00010
Giannattasio, Cristina ; Failla, Monica ; Grappiolo, Alessandra ; Calchera, Ivan ; Grieco, Niccolò ; Carugo, Stefano ; Bigoni, Marco ; Randelli, Pietro ; Peretti, Giovanni ; Mancia, Giuseppe. / Effects of physical training of the dominant arm on ipsilateral radial artery distensibility and structure. In: Journal of Hypertension. 2001 ; Vol. 19, No. 1. pp. 71-77.
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abstract = "Background: Exercise training induces cardiovascular changes that are both generalized and restricted to the microcirculation of the tissues more actively involved in the exercise itself. Whether the local effect of exercise extends to larger arteries is unknown, however. Methods: In the right and left upper limb of 17 right-handed subjects performing an asymmetric training of the upper limbs (hammer throwers and baseball players) and 16 age-matched sedentary controls, we continuously measured radial artery diameter, distensibility and wall thickness by an echotracking and a beat-to-beat finger blood pressure device. Arterial distensibility was calculated by the arctangent model of Langewouters and expressed as continuous values from diastolic to systolic blood pressure. Measurements were made: (1) in baseline conditions; (2) after release from prolonged proximal ischaemia; and (3) after an increase in radial artery blood flow caused by a short (4 min) distal ischaemia to determine the endothelial involvement in the training-induced change in arterial distensibility. Results: In athletes the radial artery distensibility was markedly greater in the right than in the left arm, the latter showing values slightly greater than those seen in the two arms of sedentary subjects. In both arms and groups radial artery distensibility increased markedly after prolonged ischaemia, the between arm and group differences being preserved, however. The radial artery response to distal short ischaemia was, on the other hand, similar in the two arms of the athletes, although greater in these subjects than in the sedentary ones. Radial artery wall thickness was greater in the trained than in the untrained arm of athletes, both values being greater than in sedentary subjects. Conclusions: Asymmetrical training of the upper limbs is accompanied by a greater distensibility of the middle-sized arteries of the more trained side. This is not associated with asymmetrical changes in endothelial structure or function. It is associated with a greater wall thickness in the trained side, suggesting that, at least in part, a training-induced asymmetrical change in wall structure (possibly with a predominance of more distensible tissues such as elastine and smooth muscle) is responsible.",
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AU - Failla, Monica

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AU - Grieco, Niccolò

AU - Carugo, Stefano

AU - Bigoni, Marco

AU - Randelli, Pietro

AU - Peretti, Giovanni

AU - Mancia, Giuseppe

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N2 - Background: Exercise training induces cardiovascular changes that are both generalized and restricted to the microcirculation of the tissues more actively involved in the exercise itself. Whether the local effect of exercise extends to larger arteries is unknown, however. Methods: In the right and left upper limb of 17 right-handed subjects performing an asymmetric training of the upper limbs (hammer throwers and baseball players) and 16 age-matched sedentary controls, we continuously measured radial artery diameter, distensibility and wall thickness by an echotracking and a beat-to-beat finger blood pressure device. Arterial distensibility was calculated by the arctangent model of Langewouters and expressed as continuous values from diastolic to systolic blood pressure. Measurements were made: (1) in baseline conditions; (2) after release from prolonged proximal ischaemia; and (3) after an increase in radial artery blood flow caused by a short (4 min) distal ischaemia to determine the endothelial involvement in the training-induced change in arterial distensibility. Results: In athletes the radial artery distensibility was markedly greater in the right than in the left arm, the latter showing values slightly greater than those seen in the two arms of sedentary subjects. In both arms and groups radial artery distensibility increased markedly after prolonged ischaemia, the between arm and group differences being preserved, however. The radial artery response to distal short ischaemia was, on the other hand, similar in the two arms of the athletes, although greater in these subjects than in the sedentary ones. Radial artery wall thickness was greater in the trained than in the untrained arm of athletes, both values being greater than in sedentary subjects. Conclusions: Asymmetrical training of the upper limbs is accompanied by a greater distensibility of the middle-sized arteries of the more trained side. This is not associated with asymmetrical changes in endothelial structure or function. It is associated with a greater wall thickness in the trained side, suggesting that, at least in part, a training-induced asymmetrical change in wall structure (possibly with a predominance of more distensible tissues such as elastine and smooth muscle) is responsible.

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