Effects of predeposit and intentional perioperative haemodilution on blood saving program in major orthopaedic surgery

L. Burbi, C. Gregoretti, B. Borghi, E. Pignotti

Research output: Contribution to journalArticlepeer-review

Abstract

In this study we evalutated the effects of predeposit and intentional perioperative haemodilution on a blood saving program in major orthopaedic surgery. We demonstrated that autologous blood phlebotomy and maintenance of optimal levels of perioperative haemodilution by delaying blood transfusion, even autologus, are efficient techniques in reducing homologous, red blood cell (HRBC) transfusion. Patients who received autologous red blood cell (ARBC) or HRBC more than one day after surgery, while having Hb values <8 g/dl, are less at risk of needing the first or additional HRBCs. In conclusion, predeposit and intentional haemodilution obtained by delaying blood transfusions, even autotransfusional, is a correct way of conducting a blood saving program (BSP) in major orthopaedic surgery. These techniques are clinically effective in avoiding or reducing HRBC transfusion.

Original languageEnglish
Pages (from-to)635-639
Number of pages5
JournalInternational Journal of Artificial Organs
Volume22
Issue number9
Publication statusPublished - Sep 1999

Keywords

  • Haemodilution
  • Major orthopaedic surgery
  • Predeposit

ASJC Scopus subject areas

  • Biophysics

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