Effects of PRES baroreceptor stimulation on thermal and mechanical pain threshold in borderline hypertensives and normotensives

H. Rau, S. Brody, W. Larbig, P. Pauli, M. Vohringer, B. Harsch, P. Kroling, N. Birbaumer

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Prior studies have noted a pain relieving effect of baroreceptor stimulation and of higher tonic blood pressure in animals and humans. The present study used a new technique for the controlled, noninvasive stimulation of human carotid baroreceptors (PRES). PRES baroreceptor manipulation was delivered to both normotensive subjects (n = 11) and medication-free labile hypertensive subjects (n = 10) during both thermal and mechanical pain. Consistent with prior research, hypertensives had a higher threshold for thermal pain than did normotensives. PRES baroreceptor manipulation had no significant effect on thermal pain threshold for either group. For the mechanical pain model, the opposite results were obtained; group pain thresholds did not differ, but there was a significant PRES baroreceptor stimulation effect of increasing pain threshold for both groups. Results are discussed in terms of specific features of the stimuli, dampening of pain in hypertensives and adaptation to pain.

Original languageEnglish
Pages (from-to)480-485
Number of pages6
JournalPsychophysiology
Volume31
Issue number5
DOIs
Publication statusPublished - 1994

Fingerprint

Pressoreceptors
Pain Threshold
Hot Temperature
Pain
Hypertension
Research

Keywords

  • Baroreceptors
  • Hypertension
  • Mechanical pain threshold
  • PRES
  • Thermal pain threshold

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)
  • Psychology(all)
  • Neuropsychology and Physiological Psychology
  • Experimental and Cognitive Psychology

Cite this

Effects of PRES baroreceptor stimulation on thermal and mechanical pain threshold in borderline hypertensives and normotensives. / Rau, H.; Brody, S.; Larbig, W.; Pauli, P.; Vohringer, M.; Harsch, B.; Kroling, P.; Birbaumer, N.

In: Psychophysiology, Vol. 31, No. 5, 1994, p. 480-485.

Research output: Contribution to journalArticle

Rau, H, Brody, S, Larbig, W, Pauli, P, Vohringer, M, Harsch, B, Kroling, P & Birbaumer, N 1994, 'Effects of PRES baroreceptor stimulation on thermal and mechanical pain threshold in borderline hypertensives and normotensives', Psychophysiology, vol. 31, no. 5, pp. 480-485. https://doi.org/10.1111/j.1469-8986.1994.tb01051.x
Rau, H. ; Brody, S. ; Larbig, W. ; Pauli, P. ; Vohringer, M. ; Harsch, B. ; Kroling, P. ; Birbaumer, N. / Effects of PRES baroreceptor stimulation on thermal and mechanical pain threshold in borderline hypertensives and normotensives. In: Psychophysiology. 1994 ; Vol. 31, No. 5. pp. 480-485.
@article{e10b138e83f64e0bbe76c5d266e2fe8e,
title = "Effects of PRES baroreceptor stimulation on thermal and mechanical pain threshold in borderline hypertensives and normotensives",
abstract = "Prior studies have noted a pain relieving effect of baroreceptor stimulation and of higher tonic blood pressure in animals and humans. The present study used a new technique for the controlled, noninvasive stimulation of human carotid baroreceptors (PRES). PRES baroreceptor manipulation was delivered to both normotensive subjects (n = 11) and medication-free labile hypertensive subjects (n = 10) during both thermal and mechanical pain. Consistent with prior research, hypertensives had a higher threshold for thermal pain than did normotensives. PRES baroreceptor manipulation had no significant effect on thermal pain threshold for either group. For the mechanical pain model, the opposite results were obtained; group pain thresholds did not differ, but there was a significant PRES baroreceptor stimulation effect of increasing pain threshold for both groups. Results are discussed in terms of specific features of the stimuli, dampening of pain in hypertensives and adaptation to pain.",
keywords = "Baroreceptors, Hypertension, Mechanical pain threshold, PRES, Thermal pain threshold",
author = "H. Rau and S. Brody and W. Larbig and P. Pauli and M. Vohringer and B. Harsch and P. Kroling and N. Birbaumer",
year = "1994",
doi = "10.1111/j.1469-8986.1994.tb01051.x",
language = "English",
volume = "31",
pages = "480--485",
journal = "Psychophysiology",
issn = "0048-5772",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - Effects of PRES baroreceptor stimulation on thermal and mechanical pain threshold in borderline hypertensives and normotensives

AU - Rau, H.

AU - Brody, S.

AU - Larbig, W.

AU - Pauli, P.

AU - Vohringer, M.

AU - Harsch, B.

AU - Kroling, P.

AU - Birbaumer, N.

PY - 1994

Y1 - 1994

N2 - Prior studies have noted a pain relieving effect of baroreceptor stimulation and of higher tonic blood pressure in animals and humans. The present study used a new technique for the controlled, noninvasive stimulation of human carotid baroreceptors (PRES). PRES baroreceptor manipulation was delivered to both normotensive subjects (n = 11) and medication-free labile hypertensive subjects (n = 10) during both thermal and mechanical pain. Consistent with prior research, hypertensives had a higher threshold for thermal pain than did normotensives. PRES baroreceptor manipulation had no significant effect on thermal pain threshold for either group. For the mechanical pain model, the opposite results were obtained; group pain thresholds did not differ, but there was a significant PRES baroreceptor stimulation effect of increasing pain threshold for both groups. Results are discussed in terms of specific features of the stimuli, dampening of pain in hypertensives and adaptation to pain.

AB - Prior studies have noted a pain relieving effect of baroreceptor stimulation and of higher tonic blood pressure in animals and humans. The present study used a new technique for the controlled, noninvasive stimulation of human carotid baroreceptors (PRES). PRES baroreceptor manipulation was delivered to both normotensive subjects (n = 11) and medication-free labile hypertensive subjects (n = 10) during both thermal and mechanical pain. Consistent with prior research, hypertensives had a higher threshold for thermal pain than did normotensives. PRES baroreceptor manipulation had no significant effect on thermal pain threshold for either group. For the mechanical pain model, the opposite results were obtained; group pain thresholds did not differ, but there was a significant PRES baroreceptor stimulation effect of increasing pain threshold for both groups. Results are discussed in terms of specific features of the stimuli, dampening of pain in hypertensives and adaptation to pain.

KW - Baroreceptors

KW - Hypertension

KW - Mechanical pain threshold

KW - PRES

KW - Thermal pain threshold

UR - http://www.scopus.com/inward/record.url?scp=0028024001&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028024001&partnerID=8YFLogxK

U2 - 10.1111/j.1469-8986.1994.tb01051.x

DO - 10.1111/j.1469-8986.1994.tb01051.x

M3 - Article

C2 - 7972602

AN - SCOPUS:0028024001

VL - 31

SP - 480

EP - 485

JO - Psychophysiology

JF - Psychophysiology

SN - 0048-5772

IS - 5

ER -