Effects of pulsed electromagnetic stimulation on patients undergoing hip revision prostheses: A randomized prospective double-blind study

Dante Dallari, Milena Fini, Gianluca Giavaresi, Nicolandrea Del Piccolo, Cesare Stagni, Luca Amendola, Nicola Rani, Saverio Gnudi, Roberto Giardino

Research output: Contribution to journalArticle

Abstract

In this prospective, randomized, double-blind study, the effect of Pulsed Electromagnetic Fields (PEMFs) was investigated in 30 subjects undergoing hip revision using the Wagner SL stem. The subjects were treated for 6 h/day up to 90 days after revision. Study end points were assessed clinically by the functional scale of Merle D'Aubigné and instrumentally by Dual-Energy X-ray Absorptiometry (DXA) at the Gruen zones. Subject improvement according to Merle D'Aubigné scale was higher (P <0.05) in subjects undergoing active stimulation compared to placebo. In analyzing the DXA findings, we subtracted for each area the postoperative bone mineral density (BMD) values from those measured at 90 days and we considered all results above 3.5% as responders. There were no significant differences in the average BMD values at each Gruen zone between the two groups both postoperatively and at 90 days investigation. In Gruen zones 5 and 6, corresponding to the medial cortex, we observed six responders (40%) in both areas in the control group, while in the stimulated group we observed 14 (93%) and 10 (66%) responders, respectively (both P <0.05). This study showed that PEMF treatment aids clinical recovery and bone stock restoration.

Original languageEnglish
Pages (from-to)423-430
Number of pages8
JournalBioelectromagnetics
Volume30
Issue number6
DOIs
Publication statusPublished - Sep 2009

Fingerprint

Hip Prosthesis
Electromagnetic Fields
Electromagnetic Phenomena
Photon Absorptiometry
Double-Blind Method
Bone Density
Hip
Placebos
Bone and Bones
Control Groups
Therapeutics

Keywords

  • Bone mineral density
  • Physical stimulation
  • X-ray

ASJC Scopus subject areas

  • Biophysics
  • Physiology
  • Radiology Nuclear Medicine and imaging

Cite this

Effects of pulsed electromagnetic stimulation on patients undergoing hip revision prostheses : A randomized prospective double-blind study. / Dallari, Dante; Fini, Milena; Giavaresi, Gianluca; Del Piccolo, Nicolandrea; Stagni, Cesare; Amendola, Luca; Rani, Nicola; Gnudi, Saverio; Giardino, Roberto.

In: Bioelectromagnetics, Vol. 30, No. 6, 09.2009, p. 423-430.

Research output: Contribution to journalArticle

Dallari, Dante ; Fini, Milena ; Giavaresi, Gianluca ; Del Piccolo, Nicolandrea ; Stagni, Cesare ; Amendola, Luca ; Rani, Nicola ; Gnudi, Saverio ; Giardino, Roberto. / Effects of pulsed electromagnetic stimulation on patients undergoing hip revision prostheses : A randomized prospective double-blind study. In: Bioelectromagnetics. 2009 ; Vol. 30, No. 6. pp. 423-430.
@article{290986c59c5a44c785fd7d496de02273,
title = "Effects of pulsed electromagnetic stimulation on patients undergoing hip revision prostheses: A randomized prospective double-blind study",
abstract = "In this prospective, randomized, double-blind study, the effect of Pulsed Electromagnetic Fields (PEMFs) was investigated in 30 subjects undergoing hip revision using the Wagner SL stem. The subjects were treated for 6 h/day up to 90 days after revision. Study end points were assessed clinically by the functional scale of Merle D'Aubign{\'e} and instrumentally by Dual-Energy X-ray Absorptiometry (DXA) at the Gruen zones. Subject improvement according to Merle D'Aubign{\'e} scale was higher (P <0.05) in subjects undergoing active stimulation compared to placebo. In analyzing the DXA findings, we subtracted for each area the postoperative bone mineral density (BMD) values from those measured at 90 days and we considered all results above 3.5{\%} as responders. There were no significant differences in the average BMD values at each Gruen zone between the two groups both postoperatively and at 90 days investigation. In Gruen zones 5 and 6, corresponding to the medial cortex, we observed six responders (40{\%}) in both areas in the control group, while in the stimulated group we observed 14 (93{\%}) and 10 (66{\%}) responders, respectively (both P <0.05). This study showed that PEMF treatment aids clinical recovery and bone stock restoration.",
keywords = "Bone mineral density, Physical stimulation, X-ray",
author = "Dante Dallari and Milena Fini and Gianluca Giavaresi and {Del Piccolo}, Nicolandrea and Cesare Stagni and Luca Amendola and Nicola Rani and Saverio Gnudi and Roberto Giardino",
year = "2009",
month = "9",
doi = "10.1002/bem.20492",
language = "English",
volume = "30",
pages = "423--430",
journal = "Bioelectromagnetics",
issn = "0197-8462",
publisher = "Wiley-Liss Inc.",
number = "6",

}

TY - JOUR

T1 - Effects of pulsed electromagnetic stimulation on patients undergoing hip revision prostheses

T2 - A randomized prospective double-blind study

AU - Dallari, Dante

AU - Fini, Milena

AU - Giavaresi, Gianluca

AU - Del Piccolo, Nicolandrea

AU - Stagni, Cesare

AU - Amendola, Luca

AU - Rani, Nicola

AU - Gnudi, Saverio

AU - Giardino, Roberto

PY - 2009/9

Y1 - 2009/9

N2 - In this prospective, randomized, double-blind study, the effect of Pulsed Electromagnetic Fields (PEMFs) was investigated in 30 subjects undergoing hip revision using the Wagner SL stem. The subjects were treated for 6 h/day up to 90 days after revision. Study end points were assessed clinically by the functional scale of Merle D'Aubigné and instrumentally by Dual-Energy X-ray Absorptiometry (DXA) at the Gruen zones. Subject improvement according to Merle D'Aubigné scale was higher (P <0.05) in subjects undergoing active stimulation compared to placebo. In analyzing the DXA findings, we subtracted for each area the postoperative bone mineral density (BMD) values from those measured at 90 days and we considered all results above 3.5% as responders. There were no significant differences in the average BMD values at each Gruen zone between the two groups both postoperatively and at 90 days investigation. In Gruen zones 5 and 6, corresponding to the medial cortex, we observed six responders (40%) in both areas in the control group, while in the stimulated group we observed 14 (93%) and 10 (66%) responders, respectively (both P <0.05). This study showed that PEMF treatment aids clinical recovery and bone stock restoration.

AB - In this prospective, randomized, double-blind study, the effect of Pulsed Electromagnetic Fields (PEMFs) was investigated in 30 subjects undergoing hip revision using the Wagner SL stem. The subjects were treated for 6 h/day up to 90 days after revision. Study end points were assessed clinically by the functional scale of Merle D'Aubigné and instrumentally by Dual-Energy X-ray Absorptiometry (DXA) at the Gruen zones. Subject improvement according to Merle D'Aubigné scale was higher (P <0.05) in subjects undergoing active stimulation compared to placebo. In analyzing the DXA findings, we subtracted for each area the postoperative bone mineral density (BMD) values from those measured at 90 days and we considered all results above 3.5% as responders. There were no significant differences in the average BMD values at each Gruen zone between the two groups both postoperatively and at 90 days investigation. In Gruen zones 5 and 6, corresponding to the medial cortex, we observed six responders (40%) in both areas in the control group, while in the stimulated group we observed 14 (93%) and 10 (66%) responders, respectively (both P <0.05). This study showed that PEMF treatment aids clinical recovery and bone stock restoration.

KW - Bone mineral density

KW - Physical stimulation

KW - X-ray

UR - http://www.scopus.com/inward/record.url?scp=68149137014&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=68149137014&partnerID=8YFLogxK

U2 - 10.1002/bem.20492

DO - 10.1002/bem.20492

M3 - Article

C2 - 19384914

AN - SCOPUS:68149137014

VL - 30

SP - 423

EP - 430

JO - Bioelectromagnetics

JF - Bioelectromagnetics

SN - 0197-8462

IS - 6

ER -