Effects of pulsed electromagnetic stimulation on patients undergoing hip revision prostheses: A randomized prospective double-blind study

Dante Dallari, Milena Fini, Gianluca Giavaresi, Nicolandrea Del Piccolo, Cesare Stagni, Luca Amendola, Nicola Rani, Saverio Gnudi, Roberto Giardino

Research output: Contribution to journalArticle

Abstract

In this prospective, randomized, double-blind study, the effect of Pulsed Electromagnetic Fields (PEMFs) was investigated in 30 subjects undergoing hip revision using the Wagner SL stem. The subjects were treated for 6 h/day up to 90 days after revision. Study end points were assessed clinically by the functional scale of Merle D'Aubigné and instrumentally by Dual-Energy X-ray Absorptiometry (DXA) at the Gruen zones. Subject improvement according to Merle D'Aubigné scale was higher (P <0.05) in subjects undergoing active stimulation compared to placebo. In analyzing the DXA findings, we subtracted for each area the postoperative bone mineral density (BMD) values from those measured at 90 days and we considered all results above 3.5% as responders. There were no significant differences in the average BMD values at each Gruen zone between the two groups both postoperatively and at 90 days investigation. In Gruen zones 5 and 6, corresponding to the medial cortex, we observed six responders (40%) in both areas in the control group, while in the stimulated group we observed 14 (93%) and 10 (66%) responders, respectively (both P <0.05). This study showed that PEMF treatment aids clinical recovery and bone stock restoration.

Original languageEnglish
Pages (from-to)423-430
Number of pages8
JournalBioelectromagnetics
Volume30
Issue number6
DOIs
Publication statusPublished - Sep 2009

Keywords

  • Bone mineral density
  • Physical stimulation
  • X-ray

ASJC Scopus subject areas

  • Biophysics
  • Physiology
  • Radiology Nuclear Medicine and imaging

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