Effects of reference population and number of STR markers on paternity testing

Rossana Moroni, Dario Gasbarra, Elja Arjas, Matti Lukka, Ismo Ulmanen

Research output: Contribution to journalArticle

Abstract

Three sets of commonly used autosomal short tandem repeat (STR) markers (containing 15, 10 and 9 markers) and 14 databases from populations belonging to Africa, America, Asia and Europe were used to investigate how the selection of the population database and the number of considered markers would influence the statistical evidence that is usually produced to favour paternity. The study was based on a sample of 100 randomly chosen Finnish paternity trios collected during paternity testing case work and without any exclusion after use of 15 STR markers. Paternity index, power of evidence, typical paternity index and Random man excluded were computed and descriptive statistics were provided separately for trios (mother, child, alleged father) and duos (obtained from trios but not considering the genetic information of the mother). This was done for all combinations of markers and databases. In trio cases the differences between results obtained are not statistically significant. However, especially in duo cases the use of 15 STR markers is recommended.

Original languageEnglish
Pages (from-to)654-655
Number of pages2
JournalForensic Science International: Genetics Supplement Series
Volume1
Issue number1
DOIs
Publication statusPublished - Aug 2008

Keywords

  • Database effect
  • Marker effect
  • Paternity testing
  • Reference population

ASJC Scopus subject areas

  • Genetics
  • Pathology and Forensic Medicine

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