Abstract
The effects of sinoaortic denervation on systolic and diastolic blood pressure (SBP, DBP), pulse interval (PI), renal sympathetic nerve activity (RSNA) and respiratory activity (RA) were investigated in conscious Wistar rats by wide-band spectral and coherence analysis. Signals were recorded during 90 minutes 6 hour after sinoaortic denervation (SAD, n=8) and in sham operated rats (n=8). After SAD animals showed higher BP mean and variability, heart rate and RSNA and lower PI variability and respiratory frequency. The rhythmic component centered at 0.4 Hz seen in RSNA in sham rats was blunted after SAD. The results suggest that PI variability and the RSNA component at 0.4 Hz depend on baroreceptors and may contribute to regulate BP within a physiological range of variability.
Original language | English |
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Title of host publication | Computers in Cardiology |
Pages | 485-488 |
Number of pages | 4 |
Publication status | Published - 2001 |
Event | Computer in Cardiology 2001 - Rotterdam, Netherlands Duration: Sep 23 2001 → Sep 26 2001 |
Other
Other | Computer in Cardiology 2001 |
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Country/Territory | Netherlands |
City | Rotterdam |
Period | 9/23/01 → 9/26/01 |
ASJC Scopus subject areas
- Software
- Cardiology and Cardiovascular Medicine