Effects of sinoaortic denervation on blood pressure, pulse interval, sympathetic nerve activity and diaphragmatic electromyogram variability in conscious rats

M. R. Ushizima; E. D. Moreira; E. T. Costa; P. Castiglioni; E. M. Krieger; M. Di Rienzo; I. A. Cestari

Effects of sinoaortic denervation on blood pressure, pulse interval, sympathetic nerve activity and diaphragmatic electromyogram variability in conscious rats

M. R. Ushizima, E. D. Moreira, E. T. Costa, P. Castiglioni, E. M. Krieger, M. Di Rienzo, I. A. Cestari

Fondazione Don Carlo Gnocchi Onlus

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The effects of sinoaortic denervation on systolic and diastolic blood pressure (SBP, DBP), pulse interval (PI), renal sympathetic nerve activity (RSNA) and respiratory activity (RA) were investigated in conscious Wistar rats by wide-band spectral and coherence analysis. Signals were recorded during 90 minutes 6 hour after sinoaortic denervation (SAD, n=8) and in sham operated rats (n=8). After SAD animals showed higher BP mean and variability, heart rate and RSNA and lower PI variability and respiratory frequency. The rhythmic component centered at 0.4 Hz seen in RSNA in sham rats was blunted after SAD. The results suggest that PI variability and the RSNA component at 0.4 Hz depend on baroreceptors and may contribute to regulate BP within a physiological range of variability.

Original language	English
Title of host publication	Computers in Cardiology
Pages	485-488
Number of pages	4
Publication status	Published - 2001
Event	Computer in Cardiology 2001 - Rotterdam, Netherlands Duration: Sep 23 2001 → Sep 26 2001

Other

Other	Computer in Cardiology 2001
Country/Territory	Netherlands
City	Rotterdam
Period	9/23/01 → 9/26/01

ASJC Scopus subject areas

Software
Cardiology and Cardiovascular Medicine

Cite this

@inproceedings{1dc2d79bbfa84a92b1e710e870488b55,

title = "Effects of sinoaortic denervation on blood pressure, pulse interval, sympathetic nerve activity and diaphragmatic electromyogram variability in conscious rats",

abstract = "The effects of sinoaortic denervation on systolic and diastolic blood pressure (SBP, DBP), pulse interval (PI), renal sympathetic nerve activity (RSNA) and respiratory activity (RA) were investigated in conscious Wistar rats by wide-band spectral and coherence analysis. Signals were recorded during 90 minutes 6 hour after sinoaortic denervation (SAD, n=8) and in sham operated rats (n=8). After SAD animals showed higher BP mean and variability, heart rate and RSNA and lower PI variability and respiratory frequency. The rhythmic component centered at 0.4 Hz seen in RSNA in sham rats was blunted after SAD. The results suggest that PI variability and the RSNA component at 0.4 Hz depend on baroreceptors and may contribute to regulate BP within a physiological range of variability.",

author = "Ushizima, {M. R.} and Moreira, {E. D.} and Costa, {E. T.} and P. Castiglioni and Krieger, {E. M.} and {Di Rienzo}, M. and Cestari, {I. A.}",

year = "2001",

language = "English",

pages = "485--488",

booktitle = "Computers in Cardiology",

note = "Computer in Cardiology 2001 ; Conference date: 23-09-2001 Through 26-09-2001",

}

TY - GEN

T1 - Effects of sinoaortic denervation on blood pressure, pulse interval, sympathetic nerve activity and diaphragmatic electromyogram variability in conscious rats

AU - Ushizima, M. R.

AU - Moreira, E. D.

AU - Costa, E. T.

AU - Castiglioni, P.

AU - Krieger, E. M.

AU - Di Rienzo, M.

AU - Cestari, I. A.

PY - 2001

Y1 - 2001

N2 - The effects of sinoaortic denervation on systolic and diastolic blood pressure (SBP, DBP), pulse interval (PI), renal sympathetic nerve activity (RSNA) and respiratory activity (RA) were investigated in conscious Wistar rats by wide-band spectral and coherence analysis. Signals were recorded during 90 minutes 6 hour after sinoaortic denervation (SAD, n=8) and in sham operated rats (n=8). After SAD animals showed higher BP mean and variability, heart rate and RSNA and lower PI variability and respiratory frequency. The rhythmic component centered at 0.4 Hz seen in RSNA in sham rats was blunted after SAD. The results suggest that PI variability and the RSNA component at 0.4 Hz depend on baroreceptors and may contribute to regulate BP within a physiological range of variability.

AB - The effects of sinoaortic denervation on systolic and diastolic blood pressure (SBP, DBP), pulse interval (PI), renal sympathetic nerve activity (RSNA) and respiratory activity (RA) were investigated in conscious Wistar rats by wide-band spectral and coherence analysis. Signals were recorded during 90 minutes 6 hour after sinoaortic denervation (SAD, n=8) and in sham operated rats (n=8). After SAD animals showed higher BP mean and variability, heart rate and RSNA and lower PI variability and respiratory frequency. The rhythmic component centered at 0.4 Hz seen in RSNA in sham rats was blunted after SAD. The results suggest that PI variability and the RSNA component at 0.4 Hz depend on baroreceptors and may contribute to regulate BP within a physiological range of variability.

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M3 - Conference contribution

AN - SCOPUS:0035718273

SP - 485

EP - 488

BT - Computers in Cardiology

T2 - Computer in Cardiology 2001

Y2 - 23 September 2001 through 26 September 2001

ER -

Effects of sinoaortic denervation on blood pressure, pulse interval, sympathetic nerve activity and diaphragmatic electromyogram variability in conscious rats

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