Effects of site and menstrual cycle on barrier function and stratum corneum water-holding capacity

Enzo Berardesca, Fernanda Distante, Gian Piero Vignoli, Giacomo Rabbiosi

Research output: Contribution to journalArticle

Abstract

Background/Aims: Areas of the skin with similar anatomical structure may have different functional behaviour. In vivo barrier function and stratum corneum water-holding capacity during the menstrual cycle on two sites of the volar forearm (upper and lower) and on the anterior aspect of the thigh were evaluated using the plastic occlusion stress test (POST). Methods: 13 healthy women (age 31 ± 4) with regular menses entered the study. POST was performed by applying a plastic chamber (1.8 cm diameter) on the skin for 24 h. After removal the skin surface water loss (SSWL) was measured using an evaporimeter (EP1-Servomed, Sweden) every 5 min for 30 min. Measurements were taken on the 10th and 25th day of the menstrual cycle. Statistical analysis was performed using one-factor ANOVA for repeated measures. Free and bound water compartments of evaporation were also analysed. Results: Higher hydration and SSWL were detectable on the 25th day of the cycle. However, no significant influence of menstrual cycle was found. Significant differences between the upper and lower volar foream were detected (P <0.001). Conclusion: The differences observed were mainly related to the evaporation of bound water, confirming a different barrier function at the sites investigated; therefore, it must be taken into account that adjacent skin sites with equal structure may have different functional behaviour.

Original languageEnglish
Pages (from-to)88-90
Number of pages3
JournalSkin Research and Technology
Volume2
Issue number2
DOIs
Publication statusPublished - May 1996

Fingerprint

Menstrual Cycle
Cornea
Skin
Water
Plastics
Exercise Test
Menstruation
Thigh
Forearm
Sweden
Analysis of Variance

Keywords

  • Barrier function
  • Hydration
  • Menstrual cycle
  • Stratum corneum
  • Transepidermal water loss

ASJC Scopus subject areas

  • Dermatology

Cite this

Effects of site and menstrual cycle on barrier function and stratum corneum water-holding capacity. / Berardesca, Enzo; Distante, Fernanda; Vignoli, Gian Piero; Rabbiosi, Giacomo.

In: Skin Research and Technology, Vol. 2, No. 2, 05.1996, p. 88-90.

Research output: Contribution to journalArticle

Berardesca, Enzo ; Distante, Fernanda ; Vignoli, Gian Piero ; Rabbiosi, Giacomo. / Effects of site and menstrual cycle on barrier function and stratum corneum water-holding capacity. In: Skin Research and Technology. 1996 ; Vol. 2, No. 2. pp. 88-90.
@article{e194b8faa3b642cb995ef9bbb42c6d9d,
title = "Effects of site and menstrual cycle on barrier function and stratum corneum water-holding capacity",
abstract = "Background/Aims: Areas of the skin with similar anatomical structure may have different functional behaviour. In vivo barrier function and stratum corneum water-holding capacity during the menstrual cycle on two sites of the volar forearm (upper and lower) and on the anterior aspect of the thigh were evaluated using the plastic occlusion stress test (POST). Methods: 13 healthy women (age 31 ± 4) with regular menses entered the study. POST was performed by applying a plastic chamber (1.8 cm diameter) on the skin for 24 h. After removal the skin surface water loss (SSWL) was measured using an evaporimeter (EP1-Servomed, Sweden) every 5 min for 30 min. Measurements were taken on the 10th and 25th day of the menstrual cycle. Statistical analysis was performed using one-factor ANOVA for repeated measures. Free and bound water compartments of evaporation were also analysed. Results: Higher hydration and SSWL were detectable on the 25th day of the cycle. However, no significant influence of menstrual cycle was found. Significant differences between the upper and lower volar foream were detected (P <0.001). Conclusion: The differences observed were mainly related to the evaporation of bound water, confirming a different barrier function at the sites investigated; therefore, it must be taken into account that adjacent skin sites with equal structure may have different functional behaviour.",
keywords = "Barrier function, Hydration, Menstrual cycle, Stratum corneum, Transepidermal water loss",
author = "Enzo Berardesca and Fernanda Distante and Vignoli, {Gian Piero} and Giacomo Rabbiosi",
year = "1996",
month = "5",
doi = "10.1111/j.1600-0846.1996.tb00065.x",
language = "English",
volume = "2",
pages = "88--90",
journal = "Skin Research and Technology",
issn = "0909-752X",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - Effects of site and menstrual cycle on barrier function and stratum corneum water-holding capacity

AU - Berardesca, Enzo

AU - Distante, Fernanda

AU - Vignoli, Gian Piero

AU - Rabbiosi, Giacomo

PY - 1996/5

Y1 - 1996/5

N2 - Background/Aims: Areas of the skin with similar anatomical structure may have different functional behaviour. In vivo barrier function and stratum corneum water-holding capacity during the menstrual cycle on two sites of the volar forearm (upper and lower) and on the anterior aspect of the thigh were evaluated using the plastic occlusion stress test (POST). Methods: 13 healthy women (age 31 ± 4) with regular menses entered the study. POST was performed by applying a plastic chamber (1.8 cm diameter) on the skin for 24 h. After removal the skin surface water loss (SSWL) was measured using an evaporimeter (EP1-Servomed, Sweden) every 5 min for 30 min. Measurements were taken on the 10th and 25th day of the menstrual cycle. Statistical analysis was performed using one-factor ANOVA for repeated measures. Free and bound water compartments of evaporation were also analysed. Results: Higher hydration and SSWL were detectable on the 25th day of the cycle. However, no significant influence of menstrual cycle was found. Significant differences between the upper and lower volar foream were detected (P <0.001). Conclusion: The differences observed were mainly related to the evaporation of bound water, confirming a different barrier function at the sites investigated; therefore, it must be taken into account that adjacent skin sites with equal structure may have different functional behaviour.

AB - Background/Aims: Areas of the skin with similar anatomical structure may have different functional behaviour. In vivo barrier function and stratum corneum water-holding capacity during the menstrual cycle on two sites of the volar forearm (upper and lower) and on the anterior aspect of the thigh were evaluated using the plastic occlusion stress test (POST). Methods: 13 healthy women (age 31 ± 4) with regular menses entered the study. POST was performed by applying a plastic chamber (1.8 cm diameter) on the skin for 24 h. After removal the skin surface water loss (SSWL) was measured using an evaporimeter (EP1-Servomed, Sweden) every 5 min for 30 min. Measurements were taken on the 10th and 25th day of the menstrual cycle. Statistical analysis was performed using one-factor ANOVA for repeated measures. Free and bound water compartments of evaporation were also analysed. Results: Higher hydration and SSWL were detectable on the 25th day of the cycle. However, no significant influence of menstrual cycle was found. Significant differences between the upper and lower volar foream were detected (P <0.001). Conclusion: The differences observed were mainly related to the evaporation of bound water, confirming a different barrier function at the sites investigated; therefore, it must be taken into account that adjacent skin sites with equal structure may have different functional behaviour.

KW - Barrier function

KW - Hydration

KW - Menstrual cycle

KW - Stratum corneum

KW - Transepidermal water loss

UR - http://www.scopus.com/inward/record.url?scp=0030056678&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030056678&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0846.1996.tb00065.x

DO - 10.1111/j.1600-0846.1996.tb00065.x

M3 - Article

AN - SCOPUS:0030056678

VL - 2

SP - 88

EP - 90

JO - Skin Research and Technology

JF - Skin Research and Technology

SN - 0909-752X

IS - 2

ER -