Effects of Slow Deep Breathing at High Altitude on Oxygen Saturation, Pulmonary and Systemic Hemodynamics

Grzegorz Bilo, Miriam Revera, Maurizio Bussotti, Daniele Bonacina, Katarzyna Styczkiewicz, Gianluca Caldara, Alessia Giglio, Andrea Faini, Andrea Giuliano, Carolina Lombardi, Kalina Kawecka-Jaszcz, Giuseppe Mancia, Piergiuseppe Agostoni, Gianfranco Parati

Research output: Contribution to journalArticle

Abstract

Slow deep breathing improves blood oxygenation (SpO2) and affects hemodynamics in hypoxic patients. We investigated the ventilatory and hemodynamic effects of slow deep breathing in normal subjects at high altitude. We collected data in healthy lowlanders staying either at 4559 m for 2-3 days (Study A; N = 39) or at 5400 m for 12-16 days (Study B; N = 28). Study variables, including SpO2 and systemic and pulmonary arterial pressure, were assessed before, during and after 15 minutes of breathing at 6 breaths/min. At the end of slow breathing, an increase in SpO2 (Study A: from 80.2±7.7% to 89.5±8.2%; Study B: from 81.0±4.2% to 88.6±4.5; both p

Original languageEnglish
Article numbere49074
JournalPLoS One
Volume7
Issue number11
DOIs
Publication statusPublished - Nov 12 2012

    Fingerprint

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this