Effects of somatosensory stimulation and attention on human somatosensory cortex: An fMRI study

Tzu Ling Chen, Claudio Babiloni, Antonio Ferretti, Mauro Gianni Perrucci, Gian Luca Romani, Paolo Maria Rossini, Armando Tartaro, Cosimo Del Gratta

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

It is well known that primary and non-primary areas of human somatosensory cortex are involved in the processing of adequate deviant/rare stimuli and omission of frequent stimuli. However, the relative weight and interaction of these variables is poorly known. This functional magnetic resonance imaging (fMRI) study tested the hypothesis that somatosensory stimulus processing and attention especially interact in non-primary somatosensory areas including secondary somatosensory cortex (SII) and insula. To test this hypothesis, responses of somatosensory cortex were mapped during four conditions of an oddball paradigm: DELIVERED COUNT and IGNORE (count or ignore deviant/rare electrical stimuli, respectively); OMITTED COUNT and IGNORE (count or ignore the rare omission of frequent electrical stimuli, respectively). The deviant/rare and frequent electrical stimuli were delivered to median and ulnar nerve, respectively. It was observed that contralateral (left) primary somatosensory responses were not markedly modulated by the mentioned deviant/rare events. Furthermore, contralateral SII and insula responded to all but not OMITTED IGNORE (purely attentive) condition, whereas ipsilateral (right) SII responded to all conditions. Finally, ipsilateral insula responded to the COUNT (attentive) conditions, regardless of the physical presence of the deviant/rare stimuli. The results suggest that in somatosensory modality, bilateral SII and left (contralateral) insula reflect complex integrative processes of stimulus elaboration and attention, whereas right (ipsilateral) insula mainly sub-serves active attention to deviance within a sequence of somatosensory stimuli.

Original languageEnglish
Pages (from-to)181-188
Number of pages8
JournalNeuroImage
Volume53
Issue number1
DOIs
Publication statusPublished - Oct 2010

Fingerprint

Somatosensory Cortex
Magnetic Resonance Imaging
Ulnar Nerve
Median Nerve
Weights and Measures

Keywords

  • Attention
  • Electrical stimulation
  • FMRI
  • Oddball
  • Somatosensory

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Neurology

Cite this

Chen, T. L., Babiloni, C., Ferretti, A., Perrucci, M. G., Romani, G. L., Rossini, P. M., ... Del Gratta, C. (2010). Effects of somatosensory stimulation and attention on human somatosensory cortex: An fMRI study. NeuroImage, 53(1), 181-188. https://doi.org/10.1016/j.neuroimage.2010.06.023

Effects of somatosensory stimulation and attention on human somatosensory cortex : An fMRI study. / Chen, Tzu Ling; Babiloni, Claudio; Ferretti, Antonio; Perrucci, Mauro Gianni; Romani, Gian Luca; Rossini, Paolo Maria; Tartaro, Armando; Del Gratta, Cosimo.

In: NeuroImage, Vol. 53, No. 1, 10.2010, p. 181-188.

Research output: Contribution to journalArticle

Chen, TL, Babiloni, C, Ferretti, A, Perrucci, MG, Romani, GL, Rossini, PM, Tartaro, A & Del Gratta, C 2010, 'Effects of somatosensory stimulation and attention on human somatosensory cortex: An fMRI study', NeuroImage, vol. 53, no. 1, pp. 181-188. https://doi.org/10.1016/j.neuroimage.2010.06.023
Chen, Tzu Ling ; Babiloni, Claudio ; Ferretti, Antonio ; Perrucci, Mauro Gianni ; Romani, Gian Luca ; Rossini, Paolo Maria ; Tartaro, Armando ; Del Gratta, Cosimo. / Effects of somatosensory stimulation and attention on human somatosensory cortex : An fMRI study. In: NeuroImage. 2010 ; Vol. 53, No. 1. pp. 181-188.
@article{6bd74694371a4fb5b3ac7e8446300d3b,
title = "Effects of somatosensory stimulation and attention on human somatosensory cortex: An fMRI study",
abstract = "It is well known that primary and non-primary areas of human somatosensory cortex are involved in the processing of adequate deviant/rare stimuli and omission of frequent stimuli. However, the relative weight and interaction of these variables is poorly known. This functional magnetic resonance imaging (fMRI) study tested the hypothesis that somatosensory stimulus processing and attention especially interact in non-primary somatosensory areas including secondary somatosensory cortex (SII) and insula. To test this hypothesis, responses of somatosensory cortex were mapped during four conditions of an oddball paradigm: DELIVERED COUNT and IGNORE (count or ignore deviant/rare electrical stimuli, respectively); OMITTED COUNT and IGNORE (count or ignore the rare omission of frequent electrical stimuli, respectively). The deviant/rare and frequent electrical stimuli were delivered to median and ulnar nerve, respectively. It was observed that contralateral (left) primary somatosensory responses were not markedly modulated by the mentioned deviant/rare events. Furthermore, contralateral SII and insula responded to all but not OMITTED IGNORE (purely attentive) condition, whereas ipsilateral (right) SII responded to all conditions. Finally, ipsilateral insula responded to the COUNT (attentive) conditions, regardless of the physical presence of the deviant/rare stimuli. The results suggest that in somatosensory modality, bilateral SII and left (contralateral) insula reflect complex integrative processes of stimulus elaboration and attention, whereas right (ipsilateral) insula mainly sub-serves active attention to deviance within a sequence of somatosensory stimuli.",
keywords = "Attention, Electrical stimulation, FMRI, Oddball, Somatosensory",
author = "Chen, {Tzu Ling} and Claudio Babiloni and Antonio Ferretti and Perrucci, {Mauro Gianni} and Romani, {Gian Luca} and Rossini, {Paolo Maria} and Armando Tartaro and {Del Gratta}, Cosimo",
year = "2010",
month = "10",
doi = "10.1016/j.neuroimage.2010.06.023",
language = "English",
volume = "53",
pages = "181--188",
journal = "NeuroImage",
issn = "1053-8119",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - Effects of somatosensory stimulation and attention on human somatosensory cortex

T2 - An fMRI study

AU - Chen, Tzu Ling

AU - Babiloni, Claudio

AU - Ferretti, Antonio

AU - Perrucci, Mauro Gianni

AU - Romani, Gian Luca

AU - Rossini, Paolo Maria

AU - Tartaro, Armando

AU - Del Gratta, Cosimo

PY - 2010/10

Y1 - 2010/10

N2 - It is well known that primary and non-primary areas of human somatosensory cortex are involved in the processing of adequate deviant/rare stimuli and omission of frequent stimuli. However, the relative weight and interaction of these variables is poorly known. This functional magnetic resonance imaging (fMRI) study tested the hypothesis that somatosensory stimulus processing and attention especially interact in non-primary somatosensory areas including secondary somatosensory cortex (SII) and insula. To test this hypothesis, responses of somatosensory cortex were mapped during four conditions of an oddball paradigm: DELIVERED COUNT and IGNORE (count or ignore deviant/rare electrical stimuli, respectively); OMITTED COUNT and IGNORE (count or ignore the rare omission of frequent electrical stimuli, respectively). The deviant/rare and frequent electrical stimuli were delivered to median and ulnar nerve, respectively. It was observed that contralateral (left) primary somatosensory responses were not markedly modulated by the mentioned deviant/rare events. Furthermore, contralateral SII and insula responded to all but not OMITTED IGNORE (purely attentive) condition, whereas ipsilateral (right) SII responded to all conditions. Finally, ipsilateral insula responded to the COUNT (attentive) conditions, regardless of the physical presence of the deviant/rare stimuli. The results suggest that in somatosensory modality, bilateral SII and left (contralateral) insula reflect complex integrative processes of stimulus elaboration and attention, whereas right (ipsilateral) insula mainly sub-serves active attention to deviance within a sequence of somatosensory stimuli.

AB - It is well known that primary and non-primary areas of human somatosensory cortex are involved in the processing of adequate deviant/rare stimuli and omission of frequent stimuli. However, the relative weight and interaction of these variables is poorly known. This functional magnetic resonance imaging (fMRI) study tested the hypothesis that somatosensory stimulus processing and attention especially interact in non-primary somatosensory areas including secondary somatosensory cortex (SII) and insula. To test this hypothesis, responses of somatosensory cortex were mapped during four conditions of an oddball paradigm: DELIVERED COUNT and IGNORE (count or ignore deviant/rare electrical stimuli, respectively); OMITTED COUNT and IGNORE (count or ignore the rare omission of frequent electrical stimuli, respectively). The deviant/rare and frequent electrical stimuli were delivered to median and ulnar nerve, respectively. It was observed that contralateral (left) primary somatosensory responses were not markedly modulated by the mentioned deviant/rare events. Furthermore, contralateral SII and insula responded to all but not OMITTED IGNORE (purely attentive) condition, whereas ipsilateral (right) SII responded to all conditions. Finally, ipsilateral insula responded to the COUNT (attentive) conditions, regardless of the physical presence of the deviant/rare stimuli. The results suggest that in somatosensory modality, bilateral SII and left (contralateral) insula reflect complex integrative processes of stimulus elaboration and attention, whereas right (ipsilateral) insula mainly sub-serves active attention to deviance within a sequence of somatosensory stimuli.

KW - Attention

KW - Electrical stimulation

KW - FMRI

KW - Oddball

KW - Somatosensory

UR - http://www.scopus.com/inward/record.url?scp=77955307992&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955307992&partnerID=8YFLogxK

U2 - 10.1016/j.neuroimage.2010.06.023

DO - 10.1016/j.neuroimage.2010.06.023

M3 - Article

C2 - 20598908

AN - SCOPUS:77955307992

VL - 53

SP - 181

EP - 188

JO - NeuroImage

JF - NeuroImage

SN - 1053-8119

IS - 1

ER -