Effects of Staphylococcus aureus lysozyme on human fibroblasts

G. Satta, P. E. Varaldo, B. Azzarone, C. A. Romanzi

Research output: Contribution to journalArticlepeer-review


The purified lysozyme excreted by Staphylococcus aureus strains promotes elongation and spreading on plastic surfaces and stimulates DNA synthesis of human fibroblasts (WI38). This enzyme also raises twofold the saturation density level of cultures of these cells. It is suggested that the primitive and main effect of lysozyme on fibroblasts is the triggering of morphogenesis.

Original languageEnglish
Pages (from-to)525-533
Number of pages9
JournalCell Biology International Reports
Issue number6
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Cell Biology


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