Abstract
The effects of d-Sulpiride (25 mg i.v.) and 1-Sulpiride (25 mg i.v.) administration in the control of arterial blood pressure (ABP) and PRL-GH secretion have been analyzed in five normal male volunteers. It was observed a quite different action on ABP, 1-Sulpiride causing a long lasting hypotension and d-Sulpiride a short-lived hypertension. The correlation between ABP, heart rate and PRL-GH levels suggests a probable central cation for 1-Sulpiride and a possible peripheral action for d-Sulpiride effects on ABP.
Translated title of the contribution | Effects of sulpiride isomers in the control of blood pressure in man |
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Original language | Italian |
Pages (from-to) | 1789-1794 |
Number of pages | 6 |
Journal | Bollettino della Societa Italiana di Biologia Sperimentale |
Volume | 56 |
Issue number | 17 |
Publication status | Published - Sep 15 1980 |
ASJC Scopus subject areas
- Medicine(all)