"Azione degli isomeri della sulpiride nel controllo della pressione arteriosa nell'uomo".

Translated title of the contribution: Effects of sulpiride isomers in the control of blood pressure in man

F. Benfenati, P. Cortelli, M. de Camillis, F. Orlandi, C. Forni

Research output: Contribution to journalArticle

Abstract

The effects of d-Sulpiride (25 mg i.v.) and 1-Sulpiride (25 mg i.v.) administration in the control of arterial blood pressure (ABP) and PRL-GH secretion have been analyzed in five normal male volunteers. It was observed a quite different action on ABP, 1-Sulpiride causing a long lasting hypotension and d-Sulpiride a short-lived hypertension. The correlation between ABP, heart rate and PRL-GH levels suggests a probable central cation for 1-Sulpiride and a possible peripheral action for d-Sulpiride effects on ABP.

Original languageItalian
Pages (from-to)1789-1794
Number of pages6
JournalBollettino della Societa Italiana di Biologia Sperimentale
Volume56
Issue number17
Publication statusPublished - Sep 15 1980

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ASJC Scopus subject areas

  • Medicine(all)

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