Effects of sulpiride isomers on the control of anterior pituitary secretion in normal man

L. F. Agnati, P. Cortelli, E. De Camillis, F. Benfenati, F. Orlandi, P. Fresia

Research output: Contribution to journalArticle

Abstract

The effects of (+)- and (-)-sulpiride on anterior pituitary hormone secretion (LH, FSH, PL, hGH, TSH) have been studied in five normal men. Both (+)- and (-)-sulpiride increase PL and TSH secretion and decrease LH and FSH secretion, whereas they do not seem to affect hGH secretion. These results are discussed in view of the different action of (+)- and (-)-sulpiride on DA receptors in the forebrain with respect to DA receptors involved in the control of anterior pituitary secretion.

Original languageEnglish
Pages (from-to)289-294
Number of pages6
JournalNeuroscience Letters
Volume15
Issue number2-3
DOIs
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Neuroscience(all)

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