Effects of terguride in patients with Huntington's disease

F. Stocchi, A. Carta, A. Berardelli, A. Antonini, M. Argenta, A. Formica, A. Agnoli

Research output: Contribution to journalArticlepeer-review

Abstract

trans-Dihydrolisuride, a partial dopamine receptor agonist, was tested for its effects on chorea in a double-blind, crossover clinical study in 10 patients with Huntington's disease. In eight patients, a neurophysiological evaluation was also performed. No reduction in choreic movements or improvement in voluntary movement performance was observed. However, in some patients, there was a slight improvement in patient's alertness and a reduction of the movement reaction time.

Original languageEnglish
Pages (from-to)435-439
Number of pages5
JournalClinical Neuropharmacology
Volume12
Issue number5
Publication statusPublished - 1989

Keywords

  • chorea
  • Terguride

ASJC Scopus subject areas

  • Clinical Neurology
  • Pharmacology (medical)
  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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