trans-Dihydrolisuride, a partial dopamine receptor agonist, was tested for its effects on chorea in a double-blind, crossover clinical study in 10 patients with Huntington's disease. In eight patients, a neurophysiological evaluation was also performed. No reduction in choreic movements or improvement in voluntary movement performance was observed. However, in some patients, there was a slight improvement in patient's alertness and a reduction of the movement reaction time.
|Number of pages||5|
|Publication status||Published - 1989|
ASJC Scopus subject areas
- Clinical Neurology
- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics(all)