Effects of terguride in patients with Huntington's disease

F. Stocchi, A. Carta, A. Berardelli, A. Antonini, M. Argenta, A. Formica, A. Agnoli

Research output: Contribution to journalArticle

Abstract

trans-Dihydrolisuride, a partial dopamine receptor agonist, was tested for its effects on chorea in a double-blind, crossover clinical study in 10 patients with Huntington's disease. In eight patients, a neurophysiological evaluation was also performed. No reduction in choreic movements or improvement in voluntary movement performance was observed. However, in some patients, there was a slight improvement in patient's alertness and a reduction of the movement reaction time.

Original languageEnglish
Pages (from-to)435-439
Number of pages5
JournalClinical Neuropharmacology
Volume12
Issue number5
Publication statusPublished - 1989

Fingerprint

Huntington Disease
Chorea
Dopamine Agonists
Cross-Over Studies
dironyl

Keywords

  • chorea
  • Terguride

ASJC Scopus subject areas

  • Clinical Neurology
  • Pharmacology (medical)
  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Stocchi, F., Carta, A., Berardelli, A., Antonini, A., Argenta, M., Formica, A., & Agnoli, A. (1989). Effects of terguride in patients with Huntington's disease. Clinical Neuropharmacology, 12(5), 435-439.

Effects of terguride in patients with Huntington's disease. / Stocchi, F.; Carta, A.; Berardelli, A.; Antonini, A.; Argenta, M.; Formica, A.; Agnoli, A.

In: Clinical Neuropharmacology, Vol. 12, No. 5, 1989, p. 435-439.

Research output: Contribution to journalArticle

Stocchi, F, Carta, A, Berardelli, A, Antonini, A, Argenta, M, Formica, A & Agnoli, A 1989, 'Effects of terguride in patients with Huntington's disease', Clinical Neuropharmacology, vol. 12, no. 5, pp. 435-439.
Stocchi F, Carta A, Berardelli A, Antonini A, Argenta M, Formica A et al. Effects of terguride in patients with Huntington's disease. Clinical Neuropharmacology. 1989;12(5):435-439.
Stocchi, F. ; Carta, A. ; Berardelli, A. ; Antonini, A. ; Argenta, M. ; Formica, A. ; Agnoli, A. / Effects of terguride in patients with Huntington's disease. In: Clinical Neuropharmacology. 1989 ; Vol. 12, No. 5. pp. 435-439.
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