Effects of the chronic hypoxia on the developing blood-brain barrier in the chick embryo optic tectum.

L. Roncali, B. Nico, D. Ribatti, M. Bertossi, L. Mancini

Research output: Contribution to journalArticlepeer-review

Abstract

The blood-brain barrier to horseradish peroxidase has been investigated microscopically and ultrastructurally in the optic tectum of hatching chicken embryos which were kept under hypoxic conditions from the 3rd incubation day. The results indicated that the weakness sites of the blood-brain barrier correspond to the tight interendothelial junctions, whose breakdown allows extravasation of the marker into limited areas of the tectum wall.

Original languageEnglish
Pages (from-to)537-541
Number of pages5
JournalJournal of Submicroscopic Cytology
Volume18
Issue number3
Publication statusPublished - Jul 1986

ASJC Scopus subject areas

  • Medicine(all)

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