Effects of the chronic hypoxia on the developing blood-brain barrier in the chick embryo optic tectum.

L. Roncali; B. Nico; D. Ribatti; M. Bertossi; L. Mancini

Effects of the chronic hypoxia on the developing blood-brain barrier in the chick embryo optic tectum.

L. Roncali, B. Nico, D. Ribatti, M. Bertossi, L. Mancini

IRCCS Giovanni Paolo II

Research output: Contribution to journal › Article › peer-review

Abstract

The blood-brain barrier to horseradish peroxidase has been investigated microscopically and ultrastructurally in the optic tectum of hatching chicken embryos which were kept under hypoxic conditions from the 3rd incubation day. The results indicated that the weakness sites of the blood-brain barrier correspond to the tight interendothelial junctions, whose breakdown allows extravasation of the marker into limited areas of the tectum wall.

Original language	English
Pages (from-to)	537-541
Number of pages	5
Journal	Journal of Submicroscopic Cytology
Volume	18
Issue number	3
Publication status	Published - Jul 1986

ASJC Scopus subject areas

Medicine(all)

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title = "Effects of the chronic hypoxia on the developing blood-brain barrier in the chick embryo optic tectum.",

abstract = "The blood-brain barrier to horseradish peroxidase has been investigated microscopically and ultrastructurally in the optic tectum of hatching chicken embryos which were kept under hypoxic conditions from the 3rd incubation day. The results indicated that the weakness sites of the blood-brain barrier correspond to the tight interendothelial junctions, whose breakdown allows extravasation of the marker into limited areas of the tectum wall.",

author = "L. Roncali and B. Nico and D. Ribatti and M. Bertossi and L. Mancini",

year = "1986",

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AU - Nico, B.

AU - Ribatti, D.

AU - Bertossi, M.

AU - Mancini, L.

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N2 - The blood-brain barrier to horseradish peroxidase has been investigated microscopically and ultrastructurally in the optic tectum of hatching chicken embryos which were kept under hypoxic conditions from the 3rd incubation day. The results indicated that the weakness sites of the blood-brain barrier correspond to the tight interendothelial junctions, whose breakdown allows extravasation of the marker into limited areas of the tectum wall.

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