Effects of the chronic hypoxia on the developing blood-brain barrier in the chick embryo optic tectum.

L. Roncali, B. Nico, D. Ribatti, M. Bertossi, L. Mancini

Research output: Contribution to journalArticle

Abstract

The blood-brain barrier to horseradish peroxidase has been investigated microscopically and ultrastructurally in the optic tectum of hatching chicken embryos which were kept under hypoxic conditions from the 3rd incubation day. The results indicated that the weakness sites of the blood-brain barrier correspond to the tight interendothelial junctions, whose breakdown allows extravasation of the marker into limited areas of the tectum wall.

Original languageEnglish
Pages (from-to)537-541
Number of pages5
JournalJournal of Submicroscopic Cytology
Volume18
Issue number3
Publication statusPublished - Jul 1986

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Superior Colliculi
Chick Embryo
Blood-Brain Barrier
Tight Junctions
Horseradish Peroxidase
Chickens
Embryonic Structures
Hypoxia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Roncali, L., Nico, B., Ribatti, D., Bertossi, M., & Mancini, L. (1986). Effects of the chronic hypoxia on the developing blood-brain barrier in the chick embryo optic tectum. Journal of Submicroscopic Cytology, 18(3), 537-541.

Effects of the chronic hypoxia on the developing blood-brain barrier in the chick embryo optic tectum. / Roncali, L.; Nico, B.; Ribatti, D.; Bertossi, M.; Mancini, L.

In: Journal of Submicroscopic Cytology, Vol. 18, No. 3, 07.1986, p. 537-541.

Research output: Contribution to journalArticle

Roncali, L, Nico, B, Ribatti, D, Bertossi, M & Mancini, L 1986, 'Effects of the chronic hypoxia on the developing blood-brain barrier in the chick embryo optic tectum.', Journal of Submicroscopic Cytology, vol. 18, no. 3, pp. 537-541.
Roncali, L. ; Nico, B. ; Ribatti, D. ; Bertossi, M. ; Mancini, L. / Effects of the chronic hypoxia on the developing blood-brain barrier in the chick embryo optic tectum. In: Journal of Submicroscopic Cytology. 1986 ; Vol. 18, No. 3. pp. 537-541.
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