Effects of the lercanidipine - Enalapril combination vs. The corresponding monotherapies on home blood pressure in hypertension

Evidence from a large database

Giuseppe Mancia, Stefano Omboni, Irina Chazova, Antonio Coca, Xavier Girerd, Hermann Haller, Gianfranco Parati, Paolo Pauletto, Danuta Pupek-Musialik, Yevgeniya Svyshchenko, Alain Boye, Bruno Charrier, Yvon Couffin, Philippe Marmor, Jacques Marty, Jean Louis Navarre, Anwar Ansari, Claudia Büttner, Maximilian Kropp, Heidrun Mehling & 83 others Christine Paschen, Isabelle Schenkenberger, Helmut Schneider, Karsten Sperling, Petra Stübler, Volker Von Behren, Giuseppe Lembo, Flavio Scanferla, Leonardo Alberto Sechi, Andrzej Gębala, Andrzej Hoffmann, Krzysztof Janik, Anna Klimza-Masłowska, Barbara Kaczmarek, Piotr Koźminski, Magdalena Makowiecka-Cies̈la, Robert Mordaka, Tomasz Nowakowski, Dariusz Pasternak, Elzbieta Skibińska, Piotr Sulik, Michał Szpajer, Jolanta Walczewska, Marcin Zaczek, Agnieszka Zienciuk-Krajka, Nadezhda Alexeeva, Igor Bokarev, Iina Chazova, Alexandra Conrady, Alexander Emelyanov, Anna Galustyan, Elena Idrisova, Niyaz Khasanov, Alexander Khokhlov, Igor Libov, Olga Reshetko, German Sokurenko, Raisa Stryuk, Sergey Tereshchenko, Vasily Trofimov, Konstantin Zrazhevsky, S. Carlos Calvo, Luis De Teresa, Raimon Ferre, Juan García, Apolonia Gil, Blas Gil, Jesús Montenegro, Josefina Oliván, Jacinto Ortiz, José María Pascual, Antonio Rivera, José Antonio Sainz De Quevedo, Manuel Zúñiga, Valentin Martinez, Montserrat Pujol, Andriy Bazylevych, Olga Gyrina, Grygoriy Ignatenko, Vitaly Kazymyrko, Tetyana Khomazyuk, Lyudmyla Kononenko, Oleksii Korzh, Volodymyr Kovalenko, Oleksander Kuryata, Mykola Kushnir, Viktoriia Lishnevska, Iurii Lymar, Lidiia Ostrovska, Galyna Popik, Yuriy Rudyk, Oxana Shershnyova, Valentyna Sierkova, Borys Storozhuk, Vira Tseluyko, Mykola Vatutin, Myroslava Vayda, Vadym Vizir, Volodymyr Volkov, Olena Voloshyna, Andriy Yagensky, Svitlana Zhurba, Valerii Zorin

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objective: To compare a combination of a dihydropyridine calcium-channel blocker with an angiotensin converting enzyme inhibitor vs. monotherapy with one or the other drug and placebo for their effects on home blood pressure (HBP). Methods: After a 2-week placebo wash-out, patients with an elevated office blood pressure (BP) (diastolic 100-109 and systolic

Original languageEnglish
Pages (from-to)139-148
Number of pages10
JournalJournal of Hypertension
Volume34
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

Fingerprint

Enalapril
Databases
Blood Pressure
Hypertension
Placebo Effect
Calcium Channel Blockers
Angiotensin-Converting Enzyme Inhibitors
Placebos
Pharmaceutical Preparations
lercanidipine
1,4-dihydropyridine

Keywords

  • enalapril
  • essential hypertension
  • home blood pressure
  • lercanidipine
  • office blood pressure
  • placebo

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Effects of the lercanidipine - Enalapril combination vs. The corresponding monotherapies on home blood pressure in hypertension : Evidence from a large database. / Mancia, Giuseppe; Omboni, Stefano; Chazova, Irina; Coca, Antonio; Girerd, Xavier; Haller, Hermann; Parati, Gianfranco; Pauletto, Paolo; Pupek-Musialik, Danuta; Svyshchenko, Yevgeniya; Boye, Alain; Charrier, Bruno; Couffin, Yvon; Marmor, Philippe; Marty, Jacques; Navarre, Jean Louis; Ansari, Anwar; Büttner, Claudia; Kropp, Maximilian; Mehling, Heidrun; Paschen, Christine; Schenkenberger, Isabelle; Schneider, Helmut; Sperling, Karsten; Stübler, Petra; Von Behren, Volker; Lembo, Giuseppe; Scanferla, Flavio; Sechi, Leonardo Alberto; Gębala, Andrzej; Hoffmann, Andrzej; Janik, Krzysztof; Klimza-Masłowska, Anna; Kaczmarek, Barbara; Koźminski, Piotr; Makowiecka-Cies̈la, Magdalena; Mordaka, Robert; Nowakowski, Tomasz; Pasternak, Dariusz; Skibińska, Elzbieta; Sulik, Piotr; Szpajer, Michał; Walczewska, Jolanta; Zaczek, Marcin; Zienciuk-Krajka, Agnieszka; Alexeeva, Nadezhda; Bokarev, Igor; Chazova, Iina; Conrady, Alexandra; Emelyanov, Alexander; Galustyan, Anna; Idrisova, Elena; Khasanov, Niyaz; Khokhlov, Alexander; Libov, Igor; Reshetko, Olga; Sokurenko, German; Stryuk, Raisa; Tereshchenko, Sergey; Trofimov, Vasily; Zrazhevsky, Konstantin; Carlos Calvo, S.; De Teresa, Luis; Ferre, Raimon; García, Juan; Gil, Apolonia; Gil, Blas; Montenegro, Jesús; Oliván, Josefina; Ortiz, Jacinto; Pascual, José María; Rivera, Antonio; De Quevedo, José Antonio Sainz; Zúñiga, Manuel; Martinez, Valentin; Pujol, Montserrat; Bazylevych, Andriy; Gyrina, Olga; Ignatenko, Grygoriy; Kazymyrko, Vitaly; Khomazyuk, Tetyana; Kononenko, Lyudmyla; Korzh, Oleksii; Kovalenko, Volodymyr; Kuryata, Oleksander; Kushnir, Mykola; Lishnevska, Viktoriia; Lymar, Iurii; Ostrovska, Lidiia; Popik, Galyna; Rudyk, Yuriy; Shershnyova, Oxana; Sierkova, Valentyna; Storozhuk, Borys; Tseluyko, Vira; Vatutin, Mykola; Vayda, Myroslava; Vizir, Vadym; Volkov, Volodymyr; Voloshyna, Olena; Yagensky, Andriy; Zhurba, Svitlana; Zorin, Valerii.

In: Journal of Hypertension, Vol. 34, No. 1, 01.01.2016, p. 139-148.

Research output: Contribution to journalArticle

Mancia, G, Omboni, S, Chazova, I, Coca, A, Girerd, X, Haller, H, Parati, G, Pauletto, P, Pupek-Musialik, D, Svyshchenko, Y, Boye, A, Charrier, B, Couffin, Y, Marmor, P, Marty, J, Navarre, JL, Ansari, A, Büttner, C, Kropp, M, Mehling, H, Paschen, C, Schenkenberger, I, Schneider, H, Sperling, K, Stübler, P, Von Behren, V, Lembo, G, Scanferla, F, Sechi, LA, Gębala, A, Hoffmann, A, Janik, K, Klimza-Masłowska, A, Kaczmarek, B, Koźminski, P, Makowiecka-Cies̈la, M, Mordaka, R, Nowakowski, T, Pasternak, D, Skibińska, E, Sulik, P, Szpajer, M, Walczewska, J, Zaczek, M, Zienciuk-Krajka, A, Alexeeva, N, Bokarev, I, Chazova, I, Conrady, A, Emelyanov, A, Galustyan, A, Idrisova, E, Khasanov, N, Khokhlov, A, Libov, I, Reshetko, O, Sokurenko, G, Stryuk, R, Tereshchenko, S, Trofimov, V, Zrazhevsky, K, Carlos Calvo, S, De Teresa, L, Ferre, R, García, J, Gil, A, Gil, B, Montenegro, J, Oliván, J, Ortiz, J, Pascual, JM, Rivera, A, De Quevedo, JAS, Zúñiga, M, Martinez, V, Pujol, M, Bazylevych, A, Gyrina, O, Ignatenko, G, Kazymyrko, V, Khomazyuk, T, Kononenko, L, Korzh, O, Kovalenko, V, Kuryata, O, Kushnir, M, Lishnevska, V, Lymar, I, Ostrovska, L, Popik, G, Rudyk, Y, Shershnyova, O, Sierkova, V, Storozhuk, B, Tseluyko, V, Vatutin, M, Vayda, M, Vizir, V, Volkov, V, Voloshyna, O, Yagensky, A, Zhurba, S & Zorin, V 2016, 'Effects of the lercanidipine - Enalapril combination vs. The corresponding monotherapies on home blood pressure in hypertension: Evidence from a large database', Journal of Hypertension, vol. 34, no. 1, pp. 139-148. https://doi.org/10.1097/HJH.0000000000000767
Mancia, Giuseppe ; Omboni, Stefano ; Chazova, Irina ; Coca, Antonio ; Girerd, Xavier ; Haller, Hermann ; Parati, Gianfranco ; Pauletto, Paolo ; Pupek-Musialik, Danuta ; Svyshchenko, Yevgeniya ; Boye, Alain ; Charrier, Bruno ; Couffin, Yvon ; Marmor, Philippe ; Marty, Jacques ; Navarre, Jean Louis ; Ansari, Anwar ; Büttner, Claudia ; Kropp, Maximilian ; Mehling, Heidrun ; Paschen, Christine ; Schenkenberger, Isabelle ; Schneider, Helmut ; Sperling, Karsten ; Stübler, Petra ; Von Behren, Volker ; Lembo, Giuseppe ; Scanferla, Flavio ; Sechi, Leonardo Alberto ; Gębala, Andrzej ; Hoffmann, Andrzej ; Janik, Krzysztof ; Klimza-Masłowska, Anna ; Kaczmarek, Barbara ; Koźminski, Piotr ; Makowiecka-Cies̈la, Magdalena ; Mordaka, Robert ; Nowakowski, Tomasz ; Pasternak, Dariusz ; Skibińska, Elzbieta ; Sulik, Piotr ; Szpajer, Michał ; Walczewska, Jolanta ; Zaczek, Marcin ; Zienciuk-Krajka, Agnieszka ; Alexeeva, Nadezhda ; Bokarev, Igor ; Chazova, Iina ; Conrady, Alexandra ; Emelyanov, Alexander ; Galustyan, Anna ; Idrisova, Elena ; Khasanov, Niyaz ; Khokhlov, Alexander ; Libov, Igor ; Reshetko, Olga ; Sokurenko, German ; Stryuk, Raisa ; Tereshchenko, Sergey ; Trofimov, Vasily ; Zrazhevsky, Konstantin ; Carlos Calvo, S. ; De Teresa, Luis ; Ferre, Raimon ; García, Juan ; Gil, Apolonia ; Gil, Blas ; Montenegro, Jesús ; Oliván, Josefina ; Ortiz, Jacinto ; Pascual, José María ; Rivera, Antonio ; De Quevedo, José Antonio Sainz ; Zúñiga, Manuel ; Martinez, Valentin ; Pujol, Montserrat ; Bazylevych, Andriy ; Gyrina, Olga ; Ignatenko, Grygoriy ; Kazymyrko, Vitaly ; Khomazyuk, Tetyana ; Kononenko, Lyudmyla ; Korzh, Oleksii ; Kovalenko, Volodymyr ; Kuryata, Oleksander ; Kushnir, Mykola ; Lishnevska, Viktoriia ; Lymar, Iurii ; Ostrovska, Lidiia ; Popik, Galyna ; Rudyk, Yuriy ; Shershnyova, Oxana ; Sierkova, Valentyna ; Storozhuk, Borys ; Tseluyko, Vira ; Vatutin, Mykola ; Vayda, Myroslava ; Vizir, Vadym ; Volkov, Volodymyr ; Voloshyna, Olena ; Yagensky, Andriy ; Zhurba, Svitlana ; Zorin, Valerii. / Effects of the lercanidipine - Enalapril combination vs. The corresponding monotherapies on home blood pressure in hypertension : Evidence from a large database. In: Journal of Hypertension. 2016 ; Vol. 34, No. 1. pp. 139-148.
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T1 - Effects of the lercanidipine - Enalapril combination vs. The corresponding monotherapies on home blood pressure in hypertension

T2 - Evidence from a large database

AU - Mancia, Giuseppe

AU - Omboni, Stefano

AU - Chazova, Irina

AU - Coca, Antonio

AU - Girerd, Xavier

AU - Haller, Hermann

AU - Parati, Gianfranco

AU - Pauletto, Paolo

AU - Pupek-Musialik, Danuta

AU - Svyshchenko, Yevgeniya

AU - Boye, Alain

AU - Charrier, Bruno

AU - Couffin, Yvon

AU - Marmor, Philippe

AU - Marty, Jacques

AU - Navarre, Jean Louis

AU - Ansari, Anwar

AU - Büttner, Claudia

AU - Kropp, Maximilian

AU - Mehling, Heidrun

AU - Paschen, Christine

AU - Schenkenberger, Isabelle

AU - Schneider, Helmut

AU - Sperling, Karsten

AU - Stübler, Petra

AU - Von Behren, Volker

AU - Lembo, Giuseppe

AU - Scanferla, Flavio

AU - Sechi, Leonardo Alberto

AU - Gębala, Andrzej

AU - Hoffmann, Andrzej

AU - Janik, Krzysztof

AU - Klimza-Masłowska, Anna

AU - Kaczmarek, Barbara

AU - Koźminski, Piotr

AU - Makowiecka-Cies̈la, Magdalena

AU - Mordaka, Robert

AU - Nowakowski, Tomasz

AU - Pasternak, Dariusz

AU - Skibińska, Elzbieta

AU - Sulik, Piotr

AU - Szpajer, Michał

AU - Walczewska, Jolanta

AU - Zaczek, Marcin

AU - Zienciuk-Krajka, Agnieszka

AU - Alexeeva, Nadezhda

AU - Bokarev, Igor

AU - Chazova, Iina

AU - Conrady, Alexandra

AU - Emelyanov, Alexander

AU - Galustyan, Anna

AU - Idrisova, Elena

AU - Khasanov, Niyaz

AU - Khokhlov, Alexander

AU - Libov, Igor

AU - Reshetko, Olga

AU - Sokurenko, German

AU - Stryuk, Raisa

AU - Tereshchenko, Sergey

AU - Trofimov, Vasily

AU - Zrazhevsky, Konstantin

AU - Carlos Calvo, S.

AU - De Teresa, Luis

AU - Ferre, Raimon

AU - García, Juan

AU - Gil, Apolonia

AU - Gil, Blas

AU - Montenegro, Jesús

AU - Oliván, Josefina

AU - Ortiz, Jacinto

AU - Pascual, José María

AU - Rivera, Antonio

AU - De Quevedo, José Antonio Sainz

AU - Zúñiga, Manuel

AU - Martinez, Valentin

AU - Pujol, Montserrat

AU - Bazylevych, Andriy

AU - Gyrina, Olga

AU - Ignatenko, Grygoriy

AU - Kazymyrko, Vitaly

AU - Khomazyuk, Tetyana

AU - Kononenko, Lyudmyla

AU - Korzh, Oleksii

AU - Kovalenko, Volodymyr

AU - Kuryata, Oleksander

AU - Kushnir, Mykola

AU - Lishnevska, Viktoriia

AU - Lymar, Iurii

AU - Ostrovska, Lidiia

AU - Popik, Galyna

AU - Rudyk, Yuriy

AU - Shershnyova, Oxana

AU - Sierkova, Valentyna

AU - Storozhuk, Borys

AU - Tseluyko, Vira

AU - Vatutin, Mykola

AU - Vayda, Myroslava

AU - Vizir, Vadym

AU - Volkov, Volodymyr

AU - Voloshyna, Olena

AU - Yagensky, Andriy

AU - Zhurba, Svitlana

AU - Zorin, Valerii

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Objective: To compare a combination of a dihydropyridine calcium-channel blocker with an angiotensin converting enzyme inhibitor vs. monotherapy with one or the other drug and placebo for their effects on home blood pressure (HBP). Methods: After a 2-week placebo wash-out, patients with an elevated office blood pressure (BP) (diastolic 100-109 and systolic

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KW - enalapril

KW - essential hypertension

KW - home blood pressure

KW - lercanidipine

KW - office blood pressure

KW - placebo

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JO - Journal of Hypertension

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