Effects of treatment with embryonic and uterine tissue homogenates on Lewis lung carcinoma development

Biava Pier Mario, Antonio Fiorito, Corrado Negro, Mariangela Mariani

Research output: Contribution to journalArticlepeer-review

Abstract

Based on the hypothesis that the development of cancer is actively inhibited during embryonic life, the effects on tumor growth of homogenates of different tissues (embryos, uteri at ninth day of pregnancy, non-pregnant uteri and normal liver) were investigated in syngeneic C57BL/6 female mice. Primary tumor growth and spontaneous pulmonary metastasis formation were completely suppressed in the group of mice treated with pregnant uteri homogenates. Embryos, non-pregnant uteri and normal liver homogenates were ineffective.

Original languageEnglish
Pages (from-to)265-270
Number of pages6
JournalCancer Letters
Volume41
Issue number3
DOIs
Publication statusPublished - Aug 30 1988

Keywords

  • Embryonic tissue homogenate
  • Lewis lung carcinoma development
  • Uterine tissue homogenate

ASJC Scopus subject areas

  • Cancer Research
  • Molecular Biology
  • Oncology

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