Effects of treatment with embryonic and uterine tissue homogenates on Lewis lung carcinoma development

Biava Pier Mario; Antonio Fiorito; Corrado Negro; Mariangela Mariani

doi:10.1016/0304-3835(88)90287-X

Effects of treatment with embryonic and uterine tissue homogenates on Lewis lung carcinoma development

Biava Pier Mario, Antonio Fiorito, Corrado Negro, Mariangela Mariani

IRCCS Multimedica

Research output: Contribution to journal › Article › peer-review

Abstract

Based on the hypothesis that the development of cancer is actively inhibited during embryonic life, the effects on tumor growth of homogenates of different tissues (embryos, uteri at ninth day of pregnancy, non-pregnant uteri and normal liver) were investigated in syngeneic C57BL/6 female mice. Primary tumor growth and spontaneous pulmonary metastasis formation were completely suppressed in the group of mice treated with pregnant uteri homogenates. Embryos, non-pregnant uteri and normal liver homogenates were ineffective.

Original language	English
Pages (from-to)	265-270
Number of pages	6
Journal	Cancer Letters
Volume	41
Issue number	3
DOIs	https://doi.org/10.1016/0304-3835(88)90287-X
Publication status	Published - Aug 30 1988

Keywords

Embryonic tissue homogenate
Lewis lung carcinoma development
Uterine tissue homogenate

ASJC Scopus subject areas

Cancer Research
Molecular Biology
Oncology

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title = "Effects of treatment with embryonic and uterine tissue homogenates on Lewis lung carcinoma development",

abstract = "Based on the hypothesis that the development of cancer is actively inhibited during embryonic life, the effects on tumor growth of homogenates of different tissues (embryos, uteri at ninth day of pregnancy, non-pregnant uteri and normal liver) were investigated in syngeneic C57BL/6 female mice. Primary tumor growth and spontaneous pulmonary metastasis formation were completely suppressed in the group of mice treated with pregnant uteri homogenates. Embryos, non-pregnant uteri and normal liver homogenates were ineffective.",

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author = "{Pier Mario}, Biava and Antonio Fiorito and Corrado Negro and Mariangela Mariani",

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AU - Pier Mario, Biava

AU - Fiorito, Antonio

AU - Negro, Corrado

AU - Mariani, Mariangela

PY - 1988/8/30

Y1 - 1988/8/30

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AB - Based on the hypothesis that the development of cancer is actively inhibited during embryonic life, the effects on tumor growth of homogenates of different tissues (embryos, uteri at ninth day of pregnancy, non-pregnant uteri and normal liver) were investigated in syngeneic C57BL/6 female mice. Primary tumor growth and spontaneous pulmonary metastasis formation were completely suppressed in the group of mice treated with pregnant uteri homogenates. Embryos, non-pregnant uteri and normal liver homogenates were ineffective.

KW - Embryonic tissue homogenate

KW - Lewis lung carcinoma development

KW - Uterine tissue homogenate

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