Effects of two dosages of chlordesmethyldiazepam on mnestic-information processes in normal subjects

S. Scarone; L. Ferini Strambi; C. L. Cazzullo

Effects of two dosages of chlordesmethyldiazepam on mnestic-information processes in normal subjects

S. Scarone, L. Ferini Strambi, C. L. Cazzullo

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

A double-blind, randomized protocol was used to investigate the activity of a benzodiazepine derivative, chlordesmethyldiazepam, at two different dosages, 1 mg and 2 mg (CDDZ₁ and CDDZ₂), on mnestic functions and information processing in normal subjects. CDDZ₂ significantly impaired short-term storage of logical and associative memory, without activity on spatial and visual memory, whereas CDDZ₁ showed no difference from the placebo. Neither CDDZ₁ nor CDDZ₂ impaired the level of vigilance and the information processes the morning after use of the drug.

Original language	English
Pages (from-to)	184-191
Number of pages	8
Journal	Clinical Therapeutics
Volume	4
Issue number	3
Publication status	Published - 1981

ASJC Scopus subject areas

Pharmacology

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abstract = "A double-blind, randomized protocol was used to investigate the activity of a benzodiazepine derivative, chlordesmethyldiazepam, at two different dosages, 1 mg and 2 mg (CDDZ1 and CDDZ2), on mnestic functions and information processing in normal subjects. CDDZ2 significantly impaired short-term storage of logical and associative memory, without activity on spatial and visual memory, whereas CDDZ1 showed no difference from the placebo. Neither CDDZ1 nor CDDZ2 impaired the level of vigilance and the information processes the morning after use of the drug.",

author = "S. Scarone and {Ferini Strambi}, L. and Cazzullo, {C. L.}",

year = "1981",

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