Effects of two dosages of chlordesmethyldiazepam on mnestic-information processes in normal subjects

S. Scarone, L. Ferini Strambi, C. L. Cazzullo

Research output: Contribution to journalArticlepeer-review

Abstract

A double-blind, randomized protocol was used to investigate the activity of a benzodiazepine derivative, chlordesmethyldiazepam, at two different dosages, 1 mg and 2 mg (CDDZ1 and CDDZ2), on mnestic functions and information processing in normal subjects. CDDZ2 significantly impaired short-term storage of logical and associative memory, without activity on spatial and visual memory, whereas CDDZ1 showed no difference from the placebo. Neither CDDZ1 nor CDDZ2 impaired the level of vigilance and the information processes the morning after use of the drug.

Original languageEnglish
Pages (from-to)184-191
Number of pages8
JournalClinical Therapeutics
Volume4
Issue number3
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Pharmacology

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