Abstract
A double-blind, randomized protocol was used to investigate the activity of a benzodiazepine derivative, chlordesmethyldiazepam, at two different dosages, 1 mg and 2 mg (CDDZ1 and CDDZ2), on mnestic functions and information processing in normal subjects. CDDZ2 significantly impaired short-term storage of logical and associative memory, without activity on spatial and visual memory, whereas CDDZ1 showed no difference from the placebo. Neither CDDZ1 nor CDDZ2 impaired the level of vigilance and the information processes the morning after use of the drug.
| Original language | English |
|---|---|
| Pages (from-to) | 184-191 |
| Number of pages | 8 |
| Journal | Clinical Therapeutics |
| Volume | 4 |
| Issue number | 3 |
| Publication status | Published - 1981 |
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ASJC Scopus subject areas
- Pharmacology
Cite this
Effects of two dosages of chlordesmethyldiazepam on mnestic-information processes in normal subjects. / Scarone, S.; Ferini Strambi, L.; Cazzullo, C. L.
In: Clinical Therapeutics, Vol. 4, No. 3, 1981, p. 184-191.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of two dosages of chlordesmethyldiazepam on mnestic-information processes in normal subjects
AU - Scarone, S.
AU - Ferini Strambi, L.
AU - Cazzullo, C. L.
PY - 1981
Y1 - 1981
N2 - A double-blind, randomized protocol was used to investigate the activity of a benzodiazepine derivative, chlordesmethyldiazepam, at two different dosages, 1 mg and 2 mg (CDDZ1 and CDDZ2), on mnestic functions and information processing in normal subjects. CDDZ2 significantly impaired short-term storage of logical and associative memory, without activity on spatial and visual memory, whereas CDDZ1 showed no difference from the placebo. Neither CDDZ1 nor CDDZ2 impaired the level of vigilance and the information processes the morning after use of the drug.
AB - A double-blind, randomized protocol was used to investigate the activity of a benzodiazepine derivative, chlordesmethyldiazepam, at two different dosages, 1 mg and 2 mg (CDDZ1 and CDDZ2), on mnestic functions and information processing in normal subjects. CDDZ2 significantly impaired short-term storage of logical and associative memory, without activity on spatial and visual memory, whereas CDDZ1 showed no difference from the placebo. Neither CDDZ1 nor CDDZ2 impaired the level of vigilance and the information processes the morning after use of the drug.
UR - http://www.scopus.com/inward/record.url?scp=0019843351&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019843351&partnerID=8YFLogxK
M3 - Article
C2 - 6796270
AN - SCOPUS:0019843351
VL - 4
SP - 184
EP - 191
JO - Clinical Therapeutics
JF - Clinical Therapeutics
SN - 0149-2918
IS - 3
ER -