Effects of verbascoside biotechnologically produced by Syringa vulgaris plant cell cultures in a rodent model of colitis

Emanuela Mazzon; Emanuela Esposito; Rosanna Di Paola; Luisa Riccardi; Rocco Caminiti; Roberto Dal Toso; Giovanna Pressi; Salvatore Cuzzocrea

doi:10.1007/s00210-009-0400-5

Effects of verbascoside biotechnologically produced by Syringa vulgaris plant cell cultures in a rodent model of colitis

Emanuela Mazzon, Emanuela Esposito, Rosanna Di Paola, Luisa Riccardi, Rocco Caminiti, Roberto Dal Toso, Giovanna Pressi, Salvatore Cuzzocrea

IRCCS Centro Neurolesi "Bonino Pulejo"

Research output: Contribution to journal › Article › peer-review

Abstract

The aim of the present study was to examine the effects of verbascoside (VB) in rats subjected to experimental colitis. Colitis was induced in rats by intracolonic instillation of 2,4 dinitrobenzene sulfonic acid (DNBS; 25 mg/rat). VB was administered daily per os (0.2 and 2 mg/kg) 4 days after DNBS administration in the colon. Treatment with VB significantly (P∈

Original language	English
Pages (from-to)	79-94
Number of pages	16
Journal	Naunyn-Schmiedeberg's Archives of Pharmacology
Volume	380
Issue number	1
DOIs	https://doi.org/10.1007/s00210-009-0400-5
Publication status	Published - Jul 2009

Keywords

Colon damage
DNBS
Free radicals
Inflammation
Metalloproteinase

ASJC Scopus subject areas

Pharmacology

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10.1007/s00210-009-0400-5

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Effects of verbascoside biotechnologically produced by Syringa vulgaris plant cell cultures in a rodent model of colitis. / Mazzon, Emanuela; Esposito, Emanuela; Di Paola, Rosanna; Riccardi, Luisa; Caminiti, Rocco; Dal Toso, Roberto; Pressi, Giovanna; Cuzzocrea, Salvatore.

In: Naunyn-Schmiedeberg's Archives of Pharmacology, Vol. 380, No. 1, 07.2009, p. 79-94.

Research output: Contribution to journal › Article › peer-review

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