Effects of Vitamin E on clinic and ambulatory blood pressure in treated hypertensive patients

Gaetana Palumbo; Fausto Avanzini; Claudio Alli; Maria Carla Roncaglioni; Esio Ronchi; Mario Cristofari; Alberto Capra; Susanna Rossi; Lorenzo Nosotti; Carlo Costantini; Cesare Cavalera

doi:10.1016/S0895-7061(00)00244-2

Effects of Vitamin E on clinic and ambulatory blood pressure in treated hypertensive patients

Gaetana Palumbo, Fausto Avanzini, Claudio Alli, Maria Carla Roncaglioni, Esio Ronchi, Mario Cristofari, Alberto Capra, Susanna Rossi, Lorenzo Nosotti, Carlo Costantini, Cesare Cavalera

Istituto di Ricerche Farmacologiche "Mario Negri"

Research output: Contribution to journal › Article › peer-review

Abstract

A randomized controlled open trial studied the effect of vitamin E supplementation (300 mg/day) on clinic and 24-h ambulatory blood pressure (BP) in 142 treated hypertensive patients. After 12 weeks, clinic BP decreased whether or not patients were randomized to vitamin E. Ambulatory BP showed no change in systolic BP and a small decrease in diastolic BP (-1.6 mm Hg, 95% confidence intervals from -2.8 to -0.4 mm Hg), approaching statistical significance in comparison to the control group (P = .06). Vitamin E supplementation thus seems to have no clinically relevant effect on BP in hypertensive patients already under controlled treatment. (C) 2000 American Journal of Hypertension, Ltd.

Original language	English
Pages (from-to)	564-567
Number of pages	4
Journal	American Journal of Hypertension
Volume	13
Issue number	5 I
DOIs	https://doi.org/10.1016/S0895-7061(00)00244-2
Publication status	Published - 2000

Keywords

Ambulatory blood pressure monitoring
Blood pressure control
Hypertension
Vitamin E

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/S0895-7061(00)00244-2

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Effects of Vitamin E on clinic and ambulatory blood pressure in treated hypertensive patients. / Palumbo, Gaetana; Avanzini, Fausto; Alli, Claudio; Roncaglioni, Maria Carla; Ronchi, Esio; Cristofari, Mario; Capra, Alberto; Rossi, Susanna; Nosotti, Lorenzo; Costantini, Carlo; Cavalera, Cesare.

In: American Journal of Hypertension, Vol. 13, No. 5 I, 2000, p. 564-567.

Research output: Contribution to journal › Article › peer-review

Palumbo, Gaetana ; Avanzini, Fausto ; Alli, Claudio ; Roncaglioni, Maria Carla ; Ronchi, Esio ; Cristofari, Mario ; Capra, Alberto ; Rossi, Susanna ; Nosotti, Lorenzo ; Costantini, Carlo ; Cavalera, Cesare. / Effects of Vitamin E on clinic and ambulatory blood pressure in treated hypertensive patients. In: American Journal of Hypertension. 2000 ; Vol. 13, No. 5 I. pp. 564-567.

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abstract = "A randomized controlled open trial studied the effect of vitamin E supplementation (300 mg/day) on clinic and 24-h ambulatory blood pressure (BP) in 142 treated hypertensive patients. After 12 weeks, clinic BP decreased whether or not patients were randomized to vitamin E. Ambulatory BP showed no change in systolic BP and a small decrease in diastolic BP (-1.6 mm Hg, 95% confidence intervals from -2.8 to -0.4 mm Hg), approaching statistical significance in comparison to the control group (P = .06). Vitamin E supplementation thus seems to have no clinically relevant effect on BP in hypertensive patients already under controlled treatment. (C) 2000 American Journal of Hypertension, Ltd.",

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AU - Palumbo, Gaetana

AU - Avanzini, Fausto

AU - Alli, Claudio

AU - Roncaglioni, Maria Carla

AU - Ronchi, Esio

AU - Cristofari, Mario

AU - Capra, Alberto

AU - Rossi, Susanna

AU - Nosotti, Lorenzo

AU - Costantini, Carlo

AU - Cavalera, Cesare

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AB - A randomized controlled open trial studied the effect of vitamin E supplementation (300 mg/day) on clinic and 24-h ambulatory blood pressure (BP) in 142 treated hypertensive patients. After 12 weeks, clinic BP decreased whether or not patients were randomized to vitamin E. Ambulatory BP showed no change in systolic BP and a small decrease in diastolic BP (-1.6 mm Hg, 95% confidence intervals from -2.8 to -0.4 mm Hg), approaching statistical significance in comparison to the control group (P = .06). Vitamin E supplementation thus seems to have no clinically relevant effect on BP in hypertensive patients already under controlled treatment. (C) 2000 American Journal of Hypertension, Ltd.

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