Effects on membrane lung gas exchange of an intermittent high gas flow recruitment maneuver: preliminary data in veno-venous ECMO patients

Luigi Castagna; Alberto Zanella; Vittorio Scaravilli; Federico Magni; Salua Abd El Aziz El Sayed Deab; Michele Introna; Francesco Mojoli; Giacomo Grasselli; Antonio Pesenti; Nicolò Patroniti

doi:10.1007/s10047-015-0831-3

Effects on membrane lung gas exchange of an intermittent high gas flow recruitment maneuver: preliminary data in veno-venous ECMO patients

Luigi Castagna, Alberto Zanella, Vittorio Scaravilli, Federico Magni, Salua Abd El Aziz El Sayed Deab, Michele Introna, Francesco Mojoli, Giacomo Grasselli, Antonio Pesenti, Nicolò Patroniti

Research output: Contribution to journal › Article

Abstract

Gas exchange capabilities of polymethylpentene membrane lungs (MLs) worsen over time. ML deterioration is related to protein deposit and clot formation. Condensation and trapping of water vapor inside ML hollow fibers might affect ML performances as well. Increasing sweep gas flow (GF) could remove such fluid. The purpose of this study was to evaluate the effects on ML gas exchange of a recruitment maneuver (RM) based on a brief increase in GF, during veno-venous ECMO support. Short-term (15 min) effects of 20 RMs were assessed. RM raised ML CO₂ removal from 149 ± 37 to 174 ± 41 ml/min (p 2 transfer (155 ± 31 and 158 ± 31 ml/min before and after RM, respectively). ML outlet pCO₂ decreased after RM from 51.2 ± 5.8 to 45.8 ± 5.4 mmHg (p 2 increased from 520 ± 61 to 555 ± 51 mmHg (p 2 removal substantially, albeit temporarily. ML oxygenation performance was marginally affected.

Original language	English
Pages (from-to)	213-219
Number of pages	7
Journal	Journal of Artificial Organs
Volume	18
Issue number	3
DOIs	https://doi.org/10.1007/s10047-015-0831-3
Publication status	Published - Sep 4 2015

Keywords

Extracorporeal membrane oxygenation
Insensible
Oxygenators
Respiratory dead space
Water loss

ASJC Scopus subject areas

Biomaterials
Biomedical Engineering
Cardiology and Cardiovascular Medicine
Medicine (miscellaneous)

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Castagna, L., Zanella, A., Scaravilli, V., Magni, F., Deab, S. A. E. A. E. S., Introna, M., Mojoli, F., Grasselli, G., Pesenti, A., & Patroniti, N. (2015). Effects on membrane lung gas exchange of an intermittent high gas flow recruitment maneuver: preliminary data in veno-venous ECMO patients. Journal of Artificial Organs, 18(3), 213-219. https://doi.org/10.1007/s10047-015-0831-3

Effects on membrane lung gas exchange of an intermittent high gas flow recruitment maneuver : preliminary data in veno-venous ECMO patients. / Castagna, Luigi; Zanella, Alberto; Scaravilli, Vittorio; Magni, Federico; Deab, Salua Abd El Aziz El Sayed; Introna, Michele; Mojoli, Francesco; Grasselli, Giacomo; Pesenti, Antonio; Patroniti, Nicolò.

In: Journal of Artificial Organs, Vol. 18, No. 3, 04.09.2015, p. 213-219.

Research output: Contribution to journal › Article

Castagna, L, Zanella, A, Scaravilli, V, Magni, F, Deab, SAEAES, Introna, M, Mojoli, F, Grasselli, G, Pesenti, A & Patroniti, N 2015, 'Effects on membrane lung gas exchange of an intermittent high gas flow recruitment maneuver: preliminary data in veno-venous ECMO patients', Journal of Artificial Organs, vol. 18, no. 3, pp. 213-219. https://doi.org/10.1007/s10047-015-0831-3

Castagna, Luigi ; Zanella, Alberto ; Scaravilli, Vittorio ; Magni, Federico ; Deab, Salua Abd El Aziz El Sayed ; Introna, Michele ; Mojoli, Francesco ; Grasselli, Giacomo ; Pesenti, Antonio ; Patroniti, Nicolò. / Effects on membrane lung gas exchange of an intermittent high gas flow recruitment maneuver : preliminary data in veno-venous ECMO patients. In: Journal of Artificial Organs. 2015 ; Vol. 18, No. 3. pp. 213-219.

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