Gas exchange capabilities of polymethylpentene membrane lungs (MLs) worsen over time. ML deterioration is related to protein deposit and clot formation. Condensation and trapping of water vapor inside ML hollow fibers might affect ML performances as well. Increasing sweep gas flow (GF) could remove such fluid. The purpose of this study was to evaluate the effects on ML gas exchange of a recruitment maneuver (RM) based on a brief increase in GF, during veno-venous ECMO support. Short-term (15 min) effects of 20 RMs were assessed. RM raised ML CO2 removal from 149 ± 37 to 174 ± 41 ml/min (p 2 transfer (155 ± 31 and 158 ± 31 ml/min before and after RM, respectively). ML outlet pCO2 decreased after RM from 51.2 ± 5.8 to 45.8 ± 5.4 mmHg (p 2 increased from 520 ± 61 to 555 ± 51 mmHg (p 2 removal substantially, albeit temporarily. ML oxygenation performance was marginally affected.
- Extracorporeal membrane oxygenation
- Respiratory dead space
- Water loss
ASJC Scopus subject areas
- Biomedical Engineering
- Cardiology and Cardiovascular Medicine
- Medicine (miscellaneous)