Abstract
This study further expands our previous observation demonstrating the usefulness of combination therapy of anti-TNF-alpha and Cyclosporine A in the treatment of rheumatoid arthritis and concurrent hepatitis C virus infection, as well its efficacy and safety in controlling HCV viremia and liver toxicity. Seven patients were included in the study; transaminase levels remained unchanged, HCV RNA serum levels decreased significantly and DAS 28 significantly improved after twelve month follow-up. No side effects were registered.
| Original language | English |
|---|---|
| Pages (from-to) | 543-546 |
| Number of pages | 4 |
| Journal | International Journal of Immunopathology and Pharmacology |
| Volume | 22 |
| Issue number | 2 |
| Publication status | Published - Apr 2009 |
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Keywords
- Anti TNF- α
- CsA
- HCV
- Rheumatoid arthritis
ASJC Scopus subject areas
- Immunology
- Immunology and Allergy
- Pharmacology
Cite this
Efficacy and safety of anti-TNF-α therapy combined with cyclosporine a in patients with rheumatoid arthritis and concomitant hepatitis C virus infection. / Giannitti, C.; Benucci, M.; Caporali, R.; Manganelli, S.; Bellisai, F.; Sebastiani, G. D.; Galeazzi, Mauro.
In: International Journal of Immunopathology and Pharmacology, Vol. 22, No. 2, 04.2009, p. 543-546.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Efficacy and safety of anti-TNF-α therapy combined with cyclosporine a in patients with rheumatoid arthritis and concomitant hepatitis C virus infection
AU - Giannitti, C.
AU - Benucci, M.
AU - Caporali, R.
AU - Manganelli, S.
AU - Bellisai, F.
AU - Sebastiani, G. D.
AU - Galeazzi, Mauro
PY - 2009/4
Y1 - 2009/4
N2 - This study further expands our previous observation demonstrating the usefulness of combination therapy of anti-TNF-alpha and Cyclosporine A in the treatment of rheumatoid arthritis and concurrent hepatitis C virus infection, as well its efficacy and safety in controlling HCV viremia and liver toxicity. Seven patients were included in the study; transaminase levels remained unchanged, HCV RNA serum levels decreased significantly and DAS 28 significantly improved after twelve month follow-up. No side effects were registered.
AB - This study further expands our previous observation demonstrating the usefulness of combination therapy of anti-TNF-alpha and Cyclosporine A in the treatment of rheumatoid arthritis and concurrent hepatitis C virus infection, as well its efficacy and safety in controlling HCV viremia and liver toxicity. Seven patients were included in the study; transaminase levels remained unchanged, HCV RNA serum levels decreased significantly and DAS 28 significantly improved after twelve month follow-up. No side effects were registered.
KW - Anti TNF- α
KW - CsA
KW - HCV
KW - Rheumatoid arthritis
UR - http://www.scopus.com/inward/record.url?scp=67650477221&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67650477221&partnerID=8YFLogxK
M3 - Article
C2 - 19505408
AN - SCOPUS:67650477221
VL - 22
SP - 543
EP - 546
JO - International Journal of Immunopathology and Pharmacology
JF - International Journal of Immunopathology and Pharmacology
SN - 0394-6320
IS - 2
ER -