@article{a0531c56082d43ecb397a5961dba171e,
title = "Efficacy and Safety of Sofosbuvir/Velpatasvir in Patients With Chronic Hepatitis C Virus Infection Receiving Opioid Substitution Therapy: Analysis of Phase 3 ASTRAL Trials",
abstract = "In this analysis of the ASTRAL trials (non-opioid substitution therapy [OST], n = 984; OST, n = 51) evaluating the once-daily, pan-genotypic regimen of sofosbuvir/velpatasvir for hepatitis C virus infection, OST did not impact completion, adherence, sustained virologic response (SVR12), or safety. SVR12 was 96% (95% confidence interval, 87%, >99%) in those receiving OST.",
keywords = "Journal Article",
author = "Jason Grebely and Dore, {Gregory J.} and Stefan Zeuzem and Aspinall, {Richard J} and Raymond Fox and Lingling Han and John McNally and Anu Osinusi and Brainard, {Diana M} and Subramanian, {G. Mani} and Macky Natha and Foster, {Graham R} and Alessandra Mangia and Sulkowski, {Mark S.} and Feld, {Jordan J.}",
note = "{\textcopyright} The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.",
year = "2016",
month = dec,
day = "1",
doi = "10.1093/cid/ciw579",
language = "English",
volume = "63",
pages = "1479--1481",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "NLM (Medline)",
number = "11",
}