@article{2fb28ab6891c470491816e139a52b5f1,
title = "Efficacy and safety of two dosages of canrenone as add-on therapy in hypertensive patients taking ace-inhibitors or angiotensin II receptor blockers and hydrochlorothiazide at maximum dosage in a randomized clinical trial: The ESCAPE-IT trial",
keywords = "Angiotensin II receptor blockers, Angiotensin-converting enzyme inhibitors, Canrenone, Hydrochlorothiazide, Hypertension, aldosterone, angiotensin receptor antagonist, brain natriuretic peptide, canrenone, creatinine, dipeptidyl carboxypeptidase inhibitor, galectin 3, hydrochlorothiazide, potassium, triacylglycerol, urea, uric acid, angiotensin 1 receptor antagonist, antihypertensive agent, biological marker, mineralocorticoid antagonist, thiazide diuretic agent, add on therapy, Article, blood pressure, controlled study, drug dose comparison, drug efficacy, drug safety, drug tolerability, drug withdrawal, essential hypertension, estimated glomerular filtration rate, female, glucose blood level, heart rate, human, insulin resistance, major clinical study, male, multicenter study, open study, parallel design, phase 4 clinical trial, priority journal, pulse pressure, randomized controlled trial, side effect, urea blood level, aged, blood, clinical trial, combination drug therapy, comparative study, drug effects, hypertension, Italy, middle aged, pathophysiology, time factor, treatment outcome, Aged, Angiotensin II Type 1 Receptor Blockers, Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Biomarkers, Blood Pressure, Drug Therapy, Combination, Female, Humans, Male, Middle Aged, Mineralocorticoid Receptor Antagonists, Sodium Chloride Symporter Inhibitors, Time Factors, Treatment Outcome",
author = "G. Derosa and P. Maffioli and M. D'Avino and C. Sala and A. Mugellini and V. Vulpis and S. Felis and L. Guasti and R. Sarzani and A. Bestetti and M. Vanasia and G. Gaudio and group, {the ESCAPE-IT Trial Investigators}",
note = "Export Date: 6 February 2018 Correspondence Address: Derosa, G.; Department of Internal Medicine and Therapeutics, University of PaviaItaly; email: giuseppe.derosa@unipv.it",
year = "2017",
doi = "10.1111/1755-5922.12235",
language = "English",
volume = "35",
pages = "47--54",
journal = "Cardiovascular Therapeutics",
issn = "1755-5914",
publisher = "Blackwell Publishing Ltd",
number = "1",
}