Efficacy and toxicity of 5-fluorouracil and folates in advanced colon cancer.

E. Cortesi, A. M. Aschelter, N. Gioacchini, A. Pellegrini, L. Frati, C. Ficorella, N. Mazzei, P. Marchetti

Research output: Contribution to journalArticlepeer-review

Abstract

From February 1987 to December 1988, 34 patients with histologically confirmed advanced colorectal carcinoma were entered in a phase II trial with 5-fluorouracil (5-FU) and folinic acid, for evaluation of treatment effectiveness and toxicity. Our data confirmed that the association 5-FU and folates represents an effective and moderately tolerated palliative treatment, with diarrhea being the only dose-limiting toxicity.

Original languageEnglish
Pages (from-to)47-50
Number of pages4
JournalJournal of Chemotherapy
Volume2 Suppl 1
Publication statusPublished - Feb 1990

ASJC Scopus subject areas

  • Microbiology (medical)

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