Efficacy of a comprehensive rehabilitation programme combined with pharmacological treatment in reducing pain in a group of OA patients on a waiting list for total joint replacement

Roberto Casale, Carlo Damiani, Vanessa Rosati, Fabiola Atzeni, Piercarlo Sarzi-Puttini, Adriana S. Nica

Research output: Contribution to journalArticle

Abstract

Objectives: It has been shown that combined rehabilitation and pharmacological treatment reduce pain in subjects with osteoarthritis (OA), although the efficacy of either therapy alone may be limited. We studied the effects of a comprehensive rehabilitation programme alone and together with pharmacological treatment in relatively young OA patients awaiting total joint replacement (TJR). Methods: Forty-four OA patients randomly divided into two groups underwent three weeks of comprehensive day hospital rehabilitation treatment alone (group A) or in combination with acetaminophen 1g three times a day. Pain intensity was measured using a visual analogue scale (VAS) before and during treatment, and for four weeks afterwards, and compared between the groups using Student's t-test for unpaired data. Results: In group A, pain intensity was not reduced after the first week of treatment (T0 vs. T1: p=0.739), but was significantly reduced from the end of the second week to the end of the observation period (p

Original languageEnglish
Pages (from-to)233-239
Number of pages7
JournalClinical and Experimental Rheumatology
Volume30
Issue number2
Publication statusPublished - 2012

Keywords

  • Acetaminophen
  • Osteoarthritis
  • Pain
  • Rehabilitation
  • Total joint replacement

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

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