Abstract
Objectives: The aim of this prospective, randomized trial is to evaluate whether a corticosteroid therapy (dexamethasone sodium phosphate, 4 mg) in association with an exhaustive preoperative planning and a minimal invasive surgical technique can shorten and make up for the most common temporary disorders. Materials and methods: The trial was performed choosing the split-mouth study design, randomly assigning in each patient the side to be given the investigated drug. Fifteen volunteers were chosen (7 males and 8 females), aged between 18 and 45 years, requiring both mandibular third molar surgery belonging to the same Winter and Pell e Gregory classes. The administration of the drug was randomly assigned and concealed in opaque envelopes which were opened just before surgery, allocating the patients to two groups. The experimental group received dexamethasone (Soldesam), 4mg, as intramuscular injection. The patients' perception of the severity of their symptoms was assessed with a VAS scale and statistically evaluated. Results and conclusions: Clinical results show how local intraoperative use of dexamethasone sodium phosphate may lead to a more comfortable postoperative healing time, especially in the first hours after surgery. Lower third molars, Impaction of teeth, Corticosteroid therapy, Postoperative, complications, Oral surgery
| Original language | Italian |
|---|---|
| Pages (from-to) | 47-60 |
| Number of pages | 14 |
| Journal | Italian Oral Surgery |
| Volume | 9 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 2010 |
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ASJC Scopus subject areas
- Oral Surgery
- Orthodontics
Cite this
Efficacia della terapia cortisonica locale nella chirurgia dei terzi molari mandibolari : Studio prospettico. / Magrin, S.; Megliani, A.; Del Fabbro, M.; Taschieri, S.; Di Marco, A.; Motta Jones, J.
In: Italian Oral Surgery, Vol. 9, No. 2, 04.2010, p. 47-60.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Efficacia della terapia cortisonica locale nella chirurgia dei terzi molari mandibolari
T2 - Studio prospettico
AU - Magrin, S.
AU - Megliani, A.
AU - Del Fabbro, M.
AU - Taschieri, S.
AU - Di Marco, A.
AU - Motta Jones, J.
PY - 2010/4
Y1 - 2010/4
N2 - Objectives: The aim of this prospective, randomized trial is to evaluate whether a corticosteroid therapy (dexamethasone sodium phosphate, 4 mg) in association with an exhaustive preoperative planning and a minimal invasive surgical technique can shorten and make up for the most common temporary disorders. Materials and methods: The trial was performed choosing the split-mouth study design, randomly assigning in each patient the side to be given the investigated drug. Fifteen volunteers were chosen (7 males and 8 females), aged between 18 and 45 years, requiring both mandibular third molar surgery belonging to the same Winter and Pell e Gregory classes. The administration of the drug was randomly assigned and concealed in opaque envelopes which were opened just before surgery, allocating the patients to two groups. The experimental group received dexamethasone (Soldesam), 4mg, as intramuscular injection. The patients' perception of the severity of their symptoms was assessed with a VAS scale and statistically evaluated. Results and conclusions: Clinical results show how local intraoperative use of dexamethasone sodium phosphate may lead to a more comfortable postoperative healing time, especially in the first hours after surgery. Lower third molars, Impaction of teeth, Corticosteroid therapy, Postoperative, complications, Oral surgery
AB - Objectives: The aim of this prospective, randomized trial is to evaluate whether a corticosteroid therapy (dexamethasone sodium phosphate, 4 mg) in association with an exhaustive preoperative planning and a minimal invasive surgical technique can shorten and make up for the most common temporary disorders. Materials and methods: The trial was performed choosing the split-mouth study design, randomly assigning in each patient the side to be given the investigated drug. Fifteen volunteers were chosen (7 males and 8 females), aged between 18 and 45 years, requiring both mandibular third molar surgery belonging to the same Winter and Pell e Gregory classes. The administration of the drug was randomly assigned and concealed in opaque envelopes which were opened just before surgery, allocating the patients to two groups. The experimental group received dexamethasone (Soldesam), 4mg, as intramuscular injection. The patients' perception of the severity of their symptoms was assessed with a VAS scale and statistically evaluated. Results and conclusions: Clinical results show how local intraoperative use of dexamethasone sodium phosphate may lead to a more comfortable postoperative healing time, especially in the first hours after surgery. Lower third molars, Impaction of teeth, Corticosteroid therapy, Postoperative, complications, Oral surgery
UR - http://www.scopus.com/inward/record.url?scp=77952428511&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77952428511&partnerID=8YFLogxK
U2 - 10.1016/j.ios.2010.01.008
DO - 10.1016/j.ios.2010.01.008
M3 - Articolo
AN - SCOPUS:77952428511
VL - 9
SP - 47
EP - 60
JO - Italian Oral Surgery
JF - Italian Oral Surgery
SN - 1827-2452
IS - 2
ER -