Efficacia della terapia cortisonica locale nella chirurgia dei terzi molari mandibolari: Studio prospettico

Translated title of the contribution: Efficacy of corticosteroid therapy in lower third molar surgery: A prospective trial

S. Magrin, A. Megliani, M. Del Fabbro, S. Taschieri, A. Di Marco, J. Motta Jones

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objectives: The aim of this prospective, randomized trial is to evaluate whether a corticosteroid therapy (dexamethasone sodium phosphate, 4 mg) in association with an exhaustive preoperative planning and a minimal invasive surgical technique can shorten and make up for the most common temporary disorders. Materials and methods: The trial was performed choosing the split-mouth study design, randomly assigning in each patient the side to be given the investigated drug. Fifteen volunteers were chosen (7 males and 8 females), aged between 18 and 45 years, requiring both mandibular third molar surgery belonging to the same Winter and Pell e Gregory classes. The administration of the drug was randomly assigned and concealed in opaque envelopes which were opened just before surgery, allocating the patients to two groups. The experimental group received dexamethasone (Soldesam), 4mg, as intramuscular injection. The patients' perception of the severity of their symptoms was assessed with a VAS scale and statistically evaluated. Results and conclusions: Clinical results show how local intraoperative use of dexamethasone sodium phosphate may lead to a more comfortable postoperative healing time, especially in the first hours after surgery. Lower third molars, Impaction of teeth, Corticosteroid therapy, Postoperative, complications, Oral surgery

Original languageItalian
Pages (from-to)47-60
Number of pages14
JournalItalian Oral Surgery
Volume9
Issue number2
DOIs
Publication statusPublished - Apr 2010

Fingerprint

dexamethasone 21-phosphate
Third Molar
Adrenal Cortex Hormones
Oral Surgery
Intramuscular Injections
Pharmaceutical Preparations
Dexamethasone
Mouth
Volunteers
Tooth
Therapeutics

ASJC Scopus subject areas

  • Oral Surgery
  • Orthodontics

Cite this

Efficacia della terapia cortisonica locale nella chirurgia dei terzi molari mandibolari : Studio prospettico. / Magrin, S.; Megliani, A.; Del Fabbro, M.; Taschieri, S.; Di Marco, A.; Motta Jones, J.

In: Italian Oral Surgery, Vol. 9, No. 2, 04.2010, p. 47-60.

Research output: Contribution to journalArticle

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