Efficacy of diazoxide in preventing hypoglycemia in a child affected with hypopituitary dwarfism

A. Ventura, M. Canciani, P. Tamaro

Research output: Contribution to journalArticle

Abstract

An observation is reported of the efficacy of diazoxide (10 mg/kg 24 h) in the prevention of hypoglycemic crises in a child with growth hormone deficiency. The success of the therapy may be attributed to a reduction of glucose uptake induced by the drug, rather than to the inhibition of insulin secretion which is already depressed in subjects affected by growth hormone deficiency. The availability of a drug with no serious and irreversible side effects, capable of preventing hypoglycemic crises in patients with hormone deficiency, seems to be important whenever it is not possible to immediately start a replacement therapy.

Original languageEnglish
Pages (from-to)309-311
Number of pages3
JournalActa Paediatrica Scandinavica
Volume72
Issue number2
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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