Efficacy of lacosamide on seizures and myoclonus in a patient with epilepsia partialis continua

Maddalena Spalletti, Angela Comanducci, Alessandro Vagaggini, Luca Bucciardini, Antonello Grippo, Aldo Amantini

Research output: Contribution to journalArticlepeer-review

Abstract

A 39-year-old male with epilepsia partialis continua, refractory to first- and second-line antiepileptic drugs, is described. Lacosamide produced a progressive antiepileptic effect on Jacksonian motor seizures and subsequently on positive myoclonus, which developed into negative myoclonus before complete resolution. Our report confirms the efficacy of lacosamide on focal motor refractory status epilepticus and documents a unique effect of lacosamide on seizure semiology.

Original languageEnglish
Pages (from-to)193-196
Number of pages4
JournalEpileptic Disorders
Volume15
Issue number2
DOIs
Publication statusPublished - Jun 2013

Keywords

  • Epilepsia partialis continua
  • Lacosamide
  • Myoclonus
  • Negative myoclonus
  • Refractory status epilepticus

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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