Abstract
A 39-year-old male with epilepsia partialis continua, refractory to first- and second-line antiepileptic drugs, is described. Lacosamide produced a progressive antiepileptic effect on Jacksonian motor seizures and subsequently on positive myoclonus, which developed into negative myoclonus before complete resolution. Our report confirms the efficacy of lacosamide on focal motor refractory status epilepticus and documents a unique effect of lacosamide on seizure semiology.
| Original language | English |
|---|---|
| Pages (from-to) | 193-196 |
| Number of pages | 4 |
| Journal | Epileptic Disorders |
| Volume | 15 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Jun 2013 |
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Keywords
- Epilepsia partialis continua
- Lacosamide
- Myoclonus
- Negative myoclonus
- Refractory status epilepticus
ASJC Scopus subject areas
- Clinical Neurology
- Neurology
Cite this
Efficacy of lacosamide on seizures and myoclonus in a patient with epilepsia partialis continua. / Spalletti, Maddalena; Comanducci, Angela; Vagaggini, Alessandro; Bucciardini, Luca; Grippo, Antonello; Amantini, Aldo.
In: Epileptic Disorders, Vol. 15, No. 2, 06.2013, p. 193-196.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Efficacy of lacosamide on seizures and myoclonus in a patient with epilepsia partialis continua
AU - Spalletti, Maddalena
AU - Comanducci, Angela
AU - Vagaggini, Alessandro
AU - Bucciardini, Luca
AU - Grippo, Antonello
AU - Amantini, Aldo
PY - 2013/6
Y1 - 2013/6
N2 - A 39-year-old male with epilepsia partialis continua, refractory to first- and second-line antiepileptic drugs, is described. Lacosamide produced a progressive antiepileptic effect on Jacksonian motor seizures and subsequently on positive myoclonus, which developed into negative myoclonus before complete resolution. Our report confirms the efficacy of lacosamide on focal motor refractory status epilepticus and documents a unique effect of lacosamide on seizure semiology.
AB - A 39-year-old male with epilepsia partialis continua, refractory to first- and second-line antiepileptic drugs, is described. Lacosamide produced a progressive antiepileptic effect on Jacksonian motor seizures and subsequently on positive myoclonus, which developed into negative myoclonus before complete resolution. Our report confirms the efficacy of lacosamide on focal motor refractory status epilepticus and documents a unique effect of lacosamide on seizure semiology.
KW - Epilepsia partialis continua
KW - Lacosamide
KW - Myoclonus
KW - Negative myoclonus
KW - Refractory status epilepticus
UR - http://www.scopus.com/inward/record.url?scp=84880471901&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84880471901&partnerID=8YFLogxK
U2 - 10.1684/epd.2013.0565
DO - 10.1684/epd.2013.0565
M3 - Article
C2 - 23761109
AN - SCOPUS:84880471901
VL - 15
SP - 193
EP - 196
JO - Epileptic Disorders
JF - Epileptic Disorders
SN - 1294-9361
IS - 2
ER -