Partial epilepsies with seizures characterized by sudden fall (epileptic drop attacks: EDA) have a poor prognosis: seizures are very frequent, usually drug-resistant, provoking multiple body and head injuries. Aim of this study is to evaluate the efficacy of LTG (200 to 400 mg pro die) addition in a series of 14 drug-resistant patients with partial seizures, EDA and secondary bilateral synchrony (SBS) on EEG. Secondary generalized seizures (SGS) disappeared in all cases. EDA disappeared in 7 patients and improved in 5. SBS disappeared in 7 cases. Two patients did not tolerate LTG. LTG is effective in controlling EDA. The positive result includes control of SGS and improvement of EEG tracing.
|Translated title of the contribution||Efficacy of lamotrigine (LTG) in partial epilepsies with drop seizures|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 1997|
ASJC Scopus subject areas
- Clinical Neurology