Effetto della lamotrigina sulle crisi parziali con brusca caduta

A. Rosati; P. Tinuper; C. Marini; A. Cerullo; P. Avoni; A. Baruzzi

Effetto della lamotrigina sulle crisi parziali con brusca caduta

Translated title of the contribution: Efficacy of lamotrigine (LTG) in partial epilepsies with drop seizures

A. Rosati, P. Tinuper, C. Marini, A. Cerullo, P. Avoni, A. Baruzzi

Istituto Scienze Neurologiche

Research output: Contribution to journal › Article › peer-review

Abstract

Partial epilepsies with seizures characterized by sudden fall (epileptic drop attacks: EDA) have a poor prognosis: seizures are very frequent, usually drug-resistant, provoking multiple body and head injuries. Aim of this study is to evaluate the efficacy of LTG (200 to 400 mg pro die) addition in a series of 14 drug-resistant patients with partial seizures, EDA and secondary bilateral synchrony (SBS) on EEG. Secondary generalized seizures (SGS) disappeared in all cases. EDA disappeared in 7 patients and improved in 5. SBS disappeared in 7 cases. Two patients did not tolerate LTG. LTG is effective in controlling EDA. The positive result includes control of SGS and improvement of EEG tracing.

Translated title of the contribution	Efficacy of lamotrigine (LTG) in partial epilepsies with drop seizures
Original language	Italian
Pages (from-to)	161-162
Number of pages	2
Journal	Bollettino - Lega Italiana contro l'Epilessia
Issue number	99
Publication status	Published - 1997

ASJC Scopus subject areas

Clinical Neurology

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title = "Effetto della lamotrigina sulle crisi parziali con brusca caduta",

abstract = "Partial epilepsies with seizures characterized by sudden fall (epileptic drop attacks: EDA) have a poor prognosis: seizures are very frequent, usually drug-resistant, provoking multiple body and head injuries. Aim of this study is to evaluate the efficacy of LTG (200 to 400 mg pro die) addition in a series of 14 drug-resistant patients with partial seizures, EDA and secondary bilateral synchrony (SBS) on EEG. Secondary generalized seizures (SGS) disappeared in all cases. EDA disappeared in 7 patients and improved in 5. SBS disappeared in 7 cases. Two patients did not tolerate LTG. LTG is effective in controlling EDA. The positive result includes control of SGS and improvement of EEG tracing.",

keywords = "Drop seizures, Lamotrigine, Secondary bilateral synchrony, Treatment",

author = "A. Rosati and P. Tinuper and C. Marini and A. Cerullo and P. Avoni and A. Baruzzi",

year = "1997",

language = "Italian",

pages = "161--162",

journal = "Bollettino - Lega Italiana contro l'Epilessia",

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TY - JOUR

T1 - Effetto della lamotrigina sulle crisi parziali con brusca caduta

AU - Rosati, A.

AU - Tinuper, P.

AU - Marini, C.

AU - Cerullo, A.

AU - Avoni, P.

AU - Baruzzi, A.

PY - 1997

Y1 - 1997

N2 - Partial epilepsies with seizures characterized by sudden fall (epileptic drop attacks: EDA) have a poor prognosis: seizures are very frequent, usually drug-resistant, provoking multiple body and head injuries. Aim of this study is to evaluate the efficacy of LTG (200 to 400 mg pro die) addition in a series of 14 drug-resistant patients with partial seizures, EDA and secondary bilateral synchrony (SBS) on EEG. Secondary generalized seizures (SGS) disappeared in all cases. EDA disappeared in 7 patients and improved in 5. SBS disappeared in 7 cases. Two patients did not tolerate LTG. LTG is effective in controlling EDA. The positive result includes control of SGS and improvement of EEG tracing.

AB - Partial epilepsies with seizures characterized by sudden fall (epileptic drop attacks: EDA) have a poor prognosis: seizures are very frequent, usually drug-resistant, provoking multiple body and head injuries. Aim of this study is to evaluate the efficacy of LTG (200 to 400 mg pro die) addition in a series of 14 drug-resistant patients with partial seizures, EDA and secondary bilateral synchrony (SBS) on EEG. Secondary generalized seizures (SGS) disappeared in all cases. EDA disappeared in 7 patients and improved in 5. SBS disappeared in 7 cases. Two patients did not tolerate LTG. LTG is effective in controlling EDA. The positive result includes control of SGS and improvement of EEG tracing.

KW - Drop seizures

KW - Lamotrigine

KW - Secondary bilateral synchrony

KW - Treatment

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JO - Bollettino - Lega Italiana contro l'Epilessia

JF - Bollettino - Lega Italiana contro l'Epilessia

SN - 0394-560X

IS - 99

ER -

Effetto della lamotrigina sulle crisi parziali con brusca caduta

Abstract

ASJC Scopus subject areas

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