Efficacy of low-level laser therapy in Ménière's disease: A pilot study of 10 patients

R. Teggi, C. Bellini, B. Fabiano, M. Bussi

Research output: Contribution to journalArticlepeer-review


Objective: To assess the efficacy of low-level laser therapy (LLLT) for Ménière's disease (MD). Materials and Methods: Twenty patients with unilateral MD were included in the study; all presented with uncontrolled vertigo. The patients were randomly divided into two groups: group 1 patients received LLLT 20 min a day with a 5-mW soft laser for 6 mo, while group 2 received betahistine 16 mg twice a day for 6 mo. According to American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) guidelines, the main outcome for vertigo control was considered to be the number of spells per month in the 6 mo before treatment compared with the same parameter in the 6 mo of therapy. The duration of spells expressed in minutes was also considered. Moreover, a hearing test was performed before and after therapy and results were reported as the pure tone average of 500-, 1000-, 2000-, and 3000-Hz frequencies. All results were valued at baseline, and after 3 and 6 mo of therapy. Results: Compared to baseline, the number and duration of spells were significantly reduced in both groups; statistical significance was detected for the 3-mo control in both groups (p <0.05 with the multiple pair comparison test). Betahistine seems to have a faster action in spell reduction (p <0.05 comparing the 3-mo results between the two groups). Audiometric examination did not show a statistically significant difference between the two groups. Conclusions: In our experience, LLLT seems to prevent vertigo spells in MD, although results indicate that it has a slower action than betahistine. Dose-dependent therapeutic effects could explain the last result. In our opinion, increased blood flow in the inner ear is the main mechanism leading to the therapeutic results.

Original languageEnglish
Pages (from-to)349-353
Number of pages5
JournalPhotomedicine and Laser Surgery
Issue number4
Publication statusPublished - Aug 1 2008

ASJC Scopus subject areas

  • Biomedical Engineering
  • Surgery
  • Dermatology
  • Oral Surgery


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