Efficacy of music therapy in the treatment of behavioral and psychiatric symptoms of dementia

Alfredo Raglio, Giuseppe Bellelli, Daniela Traficante, Marta Gianotti, Maria Chiara Ubezio, Daniele Villani, Marco Trabucchi

Research output: Contribution to journalArticlepeer-review


Background: Music therapy (MT) has been proposed as valid approach for behavioral and psychologic symptoms (BPSD) of dementia. However, studies demonstrating the effectiveness of this approach are lacking. Objective: To assess MT effectiveness in reducing BPSD in subjects with dementia. Method: Fifty-nine persons with dementia were enrolled in this study. All of them underwent a multidimensional assessment including Mini Mental State Examination, Barthel Index and Neuropsychiatry Inventory at enrolment and after 8, 16, and 20 weeks. Subjects were randomly assigned to experimental (n = 30) or control (n = 29) group. The MT sessions were evaluated with standardized criteria. The experimental group received 30 MT sessions (16wk of treatment), whereas the control group received educational support or entertainment activities. Results: NPI total score significantly decreased in the experimental group at 8th, 16th, and 20th weeks (interaction time × group: F3 165 = 5.06, P = 0.002). Specific BPSD (ie, delusions, agitation, anxiety, apathy, irritability, aberrant motor activity, and night-time disturbances) significantly improved. The empa-thetic relationship and the patients' active participation in the MT approach, also improved in the experimental group. Conclusions: The study shows that MT is effective to reduce BPSD in patients with moderate-severe dementia.

Original languageEnglish
Pages (from-to)158-162
Number of pages5
JournalAlzheimer Disease and Associated Disorders
Issue number2
Publication statusPublished - Apr 2008


  • Behavioral disorders
  • Dementia
  • Music therapy

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Gerontology
  • Clinical Psychology
  • Neuroscience(all)


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