Abstract
Background and aims: Several studies demonstrated that larger neck circumference (NC) in children and adolescents may help to identify obesity and cardio-metabolic abnormalities. We aimed to evaluate the correlation between NC and metabolic syndrome (MetS) risk factors and to determine the utility of this anthropometric index to identify MetS in European children. Methods and results: The present cross-sectional analysis includes 15,673 children (3-10 years) participating in the IDEFICS study. A continuous MetS (cMetS) score was calculated summing age and sex standardized z-scores of specific MetS risk factors. Receiver Operating Characteristic analysis, stratified by one-year age groups, was used to determine the ability of NC to identify children with unfavorable metabolic profile, corresponding to cMetS score ≥ 90th percentile.The areas under the curve values for NC associated with cMetS score values ≥ 90th percentile were significantly greater in girls than in boys (p <0.001), except for 5 <6 years group. For boys, optimal NC cut-off values ranged from 26.2 cm for the lowest age group (3 <4 years), up to 30.9 cm for the highest age group (9 <10 years). In girls, corresponding values varied from 24.9 cm to 29.6 cm. Conclusion: The study demonstrated the efficacy of NC in identifying European children with an unfavorable metabolic profile.
| Original language | English |
|---|---|
| Pages (from-to) | 510-516 |
| Number of pages | 7 |
| Journal | Nutrition, Metabolism and Cardiovascular Diseases |
| Volume | 26 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 1 2016 |
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Keywords
- Children
- Metabolic syndrome
- Neck circumference
- ROC curve
- Upper-body fat
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics
- Endocrinology, Diabetes and Metabolism
- Cardiology and Cardiovascular Medicine
Cite this
Efficacy of neck circumference to identify metabolic syndrome in 3-10 year-old European children : Results from IDEFICS study. / Formisano, A.; Bammann, K.; Fraterman, A.; Hadjigeorgiou, C.; Herrmann, D.; Iacoviello, L.; Marild, S.; Moreno, L. A.; Nagy, P.; Van Den Bussche, K.; Veidebaum, T.; Lauria, F.; Siani, A.
In: Nutrition, Metabolism and Cardiovascular Diseases, Vol. 26, No. 6, 01.06.2016, p. 510-516.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Efficacy of neck circumference to identify metabolic syndrome in 3-10 year-old European children
T2 - Results from IDEFICS study
AU - Formisano, A.
AU - Bammann, K.
AU - Fraterman, A.
AU - Hadjigeorgiou, C.
AU - Herrmann, D.
AU - Iacoviello, L.
AU - Marild, S.
AU - Moreno, L. A.
AU - Nagy, P.
AU - Van Den Bussche, K.
AU - Veidebaum, T.
AU - Lauria, F.
AU - Siani, A.
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Background and aims: Several studies demonstrated that larger neck circumference (NC) in children and adolescents may help to identify obesity and cardio-metabolic abnormalities. We aimed to evaluate the correlation between NC and metabolic syndrome (MetS) risk factors and to determine the utility of this anthropometric index to identify MetS in European children. Methods and results: The present cross-sectional analysis includes 15,673 children (3-10 years) participating in the IDEFICS study. A continuous MetS (cMetS) score was calculated summing age and sex standardized z-scores of specific MetS risk factors. Receiver Operating Characteristic analysis, stratified by one-year age groups, was used to determine the ability of NC to identify children with unfavorable metabolic profile, corresponding to cMetS score ≥ 90th percentile.The areas under the curve values for NC associated with cMetS score values ≥ 90th percentile were significantly greater in girls than in boys (p <0.001), except for 5 <6 years group. For boys, optimal NC cut-off values ranged from 26.2 cm for the lowest age group (3 <4 years), up to 30.9 cm for the highest age group (9 <10 years). In girls, corresponding values varied from 24.9 cm to 29.6 cm. Conclusion: The study demonstrated the efficacy of NC in identifying European children with an unfavorable metabolic profile.
AB - Background and aims: Several studies demonstrated that larger neck circumference (NC) in children and adolescents may help to identify obesity and cardio-metabolic abnormalities. We aimed to evaluate the correlation between NC and metabolic syndrome (MetS) risk factors and to determine the utility of this anthropometric index to identify MetS in European children. Methods and results: The present cross-sectional analysis includes 15,673 children (3-10 years) participating in the IDEFICS study. A continuous MetS (cMetS) score was calculated summing age and sex standardized z-scores of specific MetS risk factors. Receiver Operating Characteristic analysis, stratified by one-year age groups, was used to determine the ability of NC to identify children with unfavorable metabolic profile, corresponding to cMetS score ≥ 90th percentile.The areas under the curve values for NC associated with cMetS score values ≥ 90th percentile were significantly greater in girls than in boys (p <0.001), except for 5 <6 years group. For boys, optimal NC cut-off values ranged from 26.2 cm for the lowest age group (3 <4 years), up to 30.9 cm for the highest age group (9 <10 years). In girls, corresponding values varied from 24.9 cm to 29.6 cm. Conclusion: The study demonstrated the efficacy of NC in identifying European children with an unfavorable metabolic profile.
KW - Children
KW - Metabolic syndrome
KW - Neck circumference
KW - ROC curve
KW - Upper-body fat
UR - http://www.scopus.com/inward/record.url?scp=84963692188&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84963692188&partnerID=8YFLogxK
U2 - 10.1016/j.numecd.2016.02.012
DO - 10.1016/j.numecd.2016.02.012
M3 - Article
AN - SCOPUS:84963692188
VL - 26
SP - 510
EP - 516
JO - Nutrition, Metabolism and Cardiovascular Diseases
JF - Nutrition, Metabolism and Cardiovascular Diseases
SN - 0939-4753
IS - 6
ER -