Efficacy of permanent pacing in the management of high-risk patients with long QT syndrome

A. J. Moss, J. E. Liu, S. Gottlieb, E. H. Locati, P. J. Schwartz, J. L. Robinson

Research output: Contribution to journalArticle

Abstract

Background. From the international long QT syndrome (LQTS) study, 30 patients with corrected QT interval (QT(c)) of more than 0.44 second( 1/2 ) were identified who had permanent pacemakers implanted for management of recurrent syncope or aborted cardiac arrest. Methods and Results. Pacemakers were implanted on average 7 years after the onset of the first syncopal episode. Most of the patients were female (87%), the average age at implantation was 19 ± 13 years, the mean QT(c) was 0.55 ± 0.08 second, and 57% were receiving antiadrenergic treatment for LQTS when the pacemaker was placed. Using birth as the time origin, the median cardiac event rate was significantly (p

Original languageEnglish
Pages (from-to)1524-1529
Number of pages6
JournalCirculation
Volume84
Issue number4
Publication statusPublished - 1991

Keywords

  • Long QT syndrome
  • Pacemaker
  • Sudden cardiac death
  • Syncope

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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    Moss, A. J., Liu, J. E., Gottlieb, S., Locati, E. H., Schwartz, P. J., & Robinson, J. L. (1991). Efficacy of permanent pacing in the management of high-risk patients with long QT syndrome. Circulation, 84(4), 1524-1529.